Three naturally occurring proteins could be used to put the breaks on CRISPR/Cas9 gene-editing, acting as an “off-switch” for unwanted changes
5 things to read instead of... BCC fail
5 things to read instead of... BCC failThe email BCC can be a tricky beast to work with. As Theranos found out this week, a conversation can seem so secure, until it isn't
Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
Researchers identify potentially druggable mutant p53 proteins that promote cancer growthTruncated p53 proteins, presumed unimportant, now point to new drug targets for some of 'the hardest cancers'
"Off switch" for CRISPR/Cas9 gene editing discovered
"Off switch" for CRISPR/Cas9 gene editing discoveredThree naturally occurring proteins could be used to put the breaks on CRISPR/Cas9 gene-editing, acting as an "off-switch" for unwanted changes
The US Senate has passed the 21st Century Cures Act, a series of extensive medical funding reforms, in a 94-5 vote yesterday
New consortium set up to provide streamlined discovery and access to molecular data from patient derived xenografts
UC Berkeley bear the brunt of the judges’ questions during the oral arguements in the CRISPR patent dispute
Solution for storing genomic data promises a harmonious blend of both data privacy and accessibility
Ever since researchers connected the shortening of telomeres to aging and disease, the race has been on to understand what governs telomere length
The Short Read
Anna Middleton, Head of Society and Ethics at the Wellcome Trust Genome Campus, examines the impact of genomics upon patients and the wider public
Amalio Telenti of Human Longevity shares his frustrations with the “exome-centric” view of the world, and the meal that he would serve to Charles Darwin
Harvard Medical School geneticist and founder of multiple genomics businesses, George Church, reveals a fascination for the microscopic…
Have you read our magazine?
This issue of the magazine takes us to to the frontiers of bioinformatics and the applications that will make precision medicine a reality
A new world of genomic research, featuring Atul Butte, Roger Lasken, Stephen Kingsmore, and the genomics capital of the world
An introductory handbook to genomics. This guide aims to help ease the adoption of genomic technology in your own workplace.
What do you think?
The debate over racial bias in genomics rages on, but as FLG managing editor Carl Smith asks, are we avoiding a larger problem?
Genomic databases have a problem with racial bias, according to new research. Manuel Corpas has been looking for the same patterns in personal genomics
Straight out of San Diego, California, comes next-generation mapping for structural variations in the genome
The email BCC can be a tricky beast to work with. As Theranos found out this week, a conversation can seem so secure, until it isn’t
Guest editors Elaine Mardis and Marc Ladanyi involved in special issue of PLOS Medicine with a clinical cancer genomics focus
Which scientists, living, dead, or fictional, would you invite to a dinner party and why? The guest list for the ultimate genomics party looks pretty good!
In the press
Truncated p53 proteins, presumed unimportant, now point to new drug targets for some of ‘the hardest cancers’
Study of healthy and diseased lung tissue reveals novel targets and molecular pathways for which there are known pharmaceutical approaches
Researchers at the Babraham Institute have revealed a new understanding of the molecular switches that control gene activity in human embryonic stem cells
Illumina launch philanthropic partnership to sequence the genomes of nearly 100 rare disease patients and their parents in inaugural year
Combining pathway data resources gives a clearer view on complex biological interactions
New research shows how cells use epigenetic machinery to shut off and protect parts of the genome during reproduction
Webinars, videos and more
“Gene therapy in a box” pioneer Jennifer Adair is interviewed for the latest episode of The Stem Cell podcast
Ann Culkin, an oncology nurse at Memorial Sloan Kettering Cancer Center, discusses the importance of patient-centered care in the age of the internet
Can “any idiot” really use CRISPR? Reporter Jon Cohen sets out to try gene editing for himself, and discovers that pipette technique is everything