The development of the first automated DNA sequencers completely revolutionized the field of DNA sequencing and, eventually, made it possible to publish the first draft sequences of the human genome. Since then, a whole host of companies have developed their own approaches to DNA sequencing, resulting in a market that is filled with different possibilities and options.

These days, getting to the bottom of which sequencer will be the best option for your lab can be a nightmare, as you wade through various specification sheets, pricing models, and customer reviews. Couple that with the range of sequencers available, and it can rapidly become very difficult to identify what will be the most suitable machine for the work that you want to carry out.

Fortunately, Front Line Genomics has teamed up with Dr David Smith, Chairman of the Technology Assessment Group at the Mayo Clinic, to do the hard work for you. We’ve dug out the technicalities of all the major sequencing chemistries and put together this handy Buyers’ Guide for you to make the most informed decision possible for your particular needs.

This guide will talk you through some of the most important details that need to be considered when setting up and maintaining  a sequencing lab, including:

  • The chemistry at work in each of the main classes of sequencers
  • The cost considerations of buying, maintaining, and using different machines
  • The advantages and disadvantages of each sequencer’s output, such as possible read lengths, accuracy, and run times

If you’re someone who is interested in starting up your own sequencing lab or supplementing the technology your institution already has, then this guide is a must-have!