A universal test which can detect traces of any cancer in a patient’s bloodstream in ten minutes has been developed by scientists from the University of Queensland. As it stands the test has a sensitivity of 90%, so is able to detect 90 in 100 cases of cancer.
The World Health Organization is establishing an expert panel to set guidelines and standards on the ethical and safety issues of gene editing, the body has announced. This follows the recent revelation that a scientist in China claimed he had edited the genes of twin babies to make them HIV resistant.
Certain genetic processes of neurodegeneration, as seen in dementia, have been identified by a research team led by UCLA scientists. Two major groups of genes which create over-productions of the tau protein, which is integral to loss of neurons seen in major dementia forms, were found using mouse models of dementia, although the researchers performed additional experiments which determined the same processes occur in human brains.
A new study by the the Novo Nordisk Foundation Center for Protein Research details how CRISPR-Cas12a works, right down to the molecular level. This should make it possible to fine-tune the process to achieve better results.
He Jiankui, the Chinese scientist who stunned the world by announcing the birth of two CRISPR-edited twins this week, has claimed that another woman is already pregnant with a separate CRISPR baby.
Monitoring tumour DNA that naturally circulates in the blood of melanoma patients can not only help reveal the early stages of cancer growth and spread but also uncover new treatment options that tumour genetic analysis alone may not.
There is a large genetic component to attention deficit/hyperactivity disorder (ADHD), a study published recently in Nature Genetics has confirmed. The study assessed 20,183 individuals diagnosed with ADHD and 35,191 controls, finding variants in 12 independent loci which all contribute to ADHD.
Despite what was previously thought, some mitochondrial DNA can be inherited from fathers as well as mothers, scientists have found. A study, published recently in PNAS, began when the Cincinnati Children’s Hospital Medical Centre tested a child showing signs of fatigue and muscle pain to see if he had a mitochondrial disorder.
UC San Francisco scientists have figured out why some lung cancers become drug-resistant after initially responding to targeted therapies.
Differential brain responses to speech in toddlers with autism and poor language development associated with widespread gene expression activity in blood leukocyte cells.
APP, the gene responsible for making beta-amyloid in the brain, may be able to reshuffle its own DNA, scientists from Sanford Burnham Prebys Medical Discovery Institute in California have claimed. This development could explain why most drugs to treat Alzheimer’s, which are designed to remove beta-amyloid protein build-ups in the brain, have proven ineffective in clinical trials.
Twin girls in China have allegedly been born after having their embryonic genetic code modified using CRISPR. Chinese researcher He Jiankui, from the Southern University of Science and Technology, claims to have turned off a gene called CCR5 to offer total protection against HIV, as well as smallpox and cholera.
A DNA vaccine tested in mice reduces accumulation of both types of toxic proteins associated with Alzheimer’s disease, according to research that scientists say may pave the way to a clinical trial.
Machine learning can help healthcare workers predict whether patients may require emergency hospital admission, new study finds
A Mexican cavefish could inspire future heart failure treatments through a delicate interplay between proliferation and scarring.