One Gene Protects Against Type 2 Diabetes

6 November 2019

A mutation in one gene has been found to protect people from the onset of type 2 diabetes. Type 2 diabetes is caused by the inability of the body to regulate its blood sugar levels, as the cells are unable to produce or respond to the hormone insulin. Type 2 diabetes affects over 400 million […]

5 November 2019

Key Takeaways from Genomics England Research Conference

Genomics England and others offer a compelling vision for genomics in the UK and beyond The first Genomics England Research conference took place yesterday at the Central Hall Westminster in London. Front Line Genomics were lucky enough to have tickets, and what a fantastic and utterly unique event it was. The idea of the conference […]

5 November 2019

Dental Stem Cells Can Generate Milk Producing Cells

Dental stem cells have successfully been differentiated into milk producing mammary gland cells, which could hold applications for reconstructive breast surgery. Researchers at the University of Zurich (UZH) were able to show that dental epithelial stem cells can, under the right conditions, form non-dental tissues, namely mammary glands in female mice. Dental epithelial stem cells […]

5 November 2019

What Consumer Genetic Tests can Really Tell you About Cancer Risks

Our guest contributor Dr Neil Lamb continues his fortnighty Shareable Science Blog. Neil is the Vice President for Educational Outreach at the HudsonAlpha Institute for Biotechnology and Shareable Science will explore how genetics is relevant to people in their everyday lives.  Cancer is a disease of the genome, so it stands to reason that genetic […]

1 November 2019

Measles Can Wipe Immune System Memory

New research has shown that measles infection can cause part of the immune system memory to be deleted, taking away the body’s previously acquired immunity to other infections. It is known that measles damages the immune system, as children infected with measles are more prone to other infections once they recover. Children can show immune […]

31 October 2019

New Antibody Discovery Could Lead to Universal Flu Vaccine

A new antibody discovered in a patient that protects against multiple strains of flu could be adapted into a universal flu vaccine. Winter flu pandemics are a serious public health concern and pose a particular risk to more vulnerable people in society; including the elderly, young children, or people with compromised immune systems. Every year […]

31 October 2019

Depression Biomarker Could Enable Precision Medicine Treatments

A new biomarker that can identify depression patients experiencing a lack of motivation could be used to tailor anti-depressant drugs to patients, depending on the specific symptoms of the disease they display. Depression is one of the most common psychiatric disorders in the world and affects about 9% of the US population. However, as less […]

30 October 2019

CRISPR Turns Infectious Bacteria Against Themselves

A CRISPR encoded plasmid that causes Salmonella bacteria to make lethal cuts to its own genome could be a promising infection treatment to replace antibiotics. The gut microbiome is the ecosystem of the different types of bacteria that reside in the gut. Many gut infections are caused by one species of microbiome bacteria becoming much […]

29 October 2019

Alcohol Abuse Leaves Epigenetic Marks in Brain

Alcohol has been found to directly contribute to epigenetic markers in areas of the brain involved in learning and memory. It is therefore possible that stopping epigenetic marker deposition could be a promising therapy to treat alcohol addiction. Epigenetic markers are chemical modifications on DNA bases that alter the expression of genes without editing the […]

29 October 2019

Is There Really a Gene Drain in Deprived Areas of the UK?

A controversial study has claimed that genes associated with higher educational achievement are more prevalent in wealthier areas of the UK, apparently resulting in a ‘gene drain’ in more deprived areas of the UK. The study suggests that genetic-based social stratification is taking place, as it concludes that people with genetic traits linked to educational […]

28 October 2019

Artificial Enzymes Improve Immunotherapy Treatments

Artificial nanoenzymes have shown promise in improving both the selectivity and efficacy of immunotherapy treatment. Only a small proportion of patients see the benefits of immunotherapy as tumour cells can employ a multitude of disguises to avoid detection by the immune system. Too ensure more patients can experience the benefits of immunotherapy, new technologies are […]

28 October 2019

NIH, Gates Foundation Commit $200M to Gene-Based Cures for Sickle Cell and HIV

  Press Release from National Institute of Health  The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease (SCD) and HIV. The Bill & Melinda Gates Foundation will also invest $100 million toward this goal. The […]

25 October 2019

Oxygen Starved Cancer Cells Recruit Immune Cells to Survive

  Pancreatic cancer cells can recruit immune cells to restore their oxygen supply in response to anti-angiogenesis therapies. To maintain their nutrient and oxygen supplies tumour cells initiate the formation of new blood vessels, in a process known as angiogenesis. Many cancer therapies work by blocking angiogenesis, as the process does not usually occur in […]

25 October 2019

Environmental Genomics: A Growing Market

Metagenomics, or environmental genomics, is the study of genetic material recovered from the natural environment. Increased environmental pollution is expected to drive the metagenomics market, as tools to enable the rapid spread of chemicals through ecosystems become essential for environmental monitoring.   Environmental Genomics As microorganisms are responsible for degradation of environmental pollutants, their DNA […]

24 October 2019

New Organelle that Helps Prevent Cancer Found in Cells

A newly discovered cell organelle may prevent cancer formation by ensuring that the genetic material is sorted properly when cells divide. When cells divide by mitosis, the chromosomes split down the middle to ensure each new cell has a full copy of the genetic material. Protein tubes called microtubules are responsible for pulling the separate […]