News

Babies Born by Caesarean have Different Microbiomes

19 September 2019

Babies born by caesarean section have different gut bacteria, or microbiome, compositions to babies born vaginally, new research shows. The Microbiome is Essential to Childhood Health The gut microbiome is the ecosystem of bacteria resident in our gut. Recent research has only scratched the surface on uncovering the instrumental role the microbiome plays in our […]

18 September 2019

Cancer Cells Can Cannibilise to Survive Chemotherapy

Cancer cells can consume neighbouring cells to survive chemotherapy, new research shows. Doxorubicin is a common chemotherapy drug that works by selectively damaging the DNA of cancer cells. However, multiple cancer cells have been observed to survive doxorubicin treatment to allow a relapse of the disease. These cancer cells can enter a form of dormancy, […]

18 September 2019

Breathalyser Test Can Predict Which Patients Will Respond to Lung Cancer Immunotherapy

A newly developed ‘electronic nose’ can measure chemicals in the breath of small cancer lung patients to determine if they will respond to immunotherapy treatment. Immunotherapy is Changing Cancer Care Immunotherapy treatments harness the body’s immune system to fight the cancer cells, which is transforming the treatment of advanced stage cancers. However, only a small […]

17 September 2019

Patients Cite ‘Bad Luck’ as Third Biggest Cancer Cause

Australian cancer patients cited ‘bad luck’ or ‘fate’ as the third most common cause of their cancer, a new study has shown. The research raises worrying implications about public understanding of the disease. Cancer is caused by genetic changes that allow cells to grow and divide out of control. These genetic changes can be initiated […]

17 September 2019

Scottish Genetic Population Analysis Reflects Medieval Kingdoms

A genetic population study across Scotland has been found to reflect the boundaries of the medieval kingdoms. Population studies can give a window into human history as migrations, invasions and hardships all leave a genetic signature. For example, Britain was first invaded by the Vikings in AD 793. Interbreeding between the Vikings and the Anglo-Saxons […]

16 September 2019

Webinar: Advances in Improving HDR Efficiency for CRISPR Experiments

Front Line Genomics hosted the webinar Improved Methods for CRISPR Homology-Directed Repair Using Alt-R HDR Enhancer and ssDNA Donors with Optimized Design, which you can watch on demand for free here. The webinar described how to overcome some of the bottlenecks to using the CRISPR-Cas9 for genome manipulation and ensure its efficacy in a clinical […]

16 September 2019

Cell Hijack allows Breast Cancer Cells to Spread to Brain

Breast Cancer Metastasis Metastasis, where cancer cells break off from the primary tumour and form a new tumour elsewhere in the body, is particularly deadly for breast cancer patients. Breast cancer is prone to metastasising in the brain, which is challenging to treat. However, new research that demonstrates breast cancer cells can use exosomes to […]

13 September 2019

Cannabis Usage in Fathers Can Cause Inheritable Genetic Changes

Changing Attitudes to Cannabis Cannabis is now legalised for recreational use in 11 US states and attitudes around its risk are changing rapidly. Between 2002 and 2014, the percentage of adults in the US who perceived cannabis use as risky declined from 50% to 33%. However, as cannabis usage becomes more widespread the health risks […]

12 September 2019

Run Up to Festival of Genomics: Angelman Syndrome – Michelle Krishnan

Dr Michelle Krishnan, Translational Medicine Leader in Rare Diseases at Roche, will by speaking at our upcoming Festival of Genomics. Her talk Clinical Development in Rare Diseases: Angelman Syndrome, From Disease Biology Insights to Genomic Medicine, will explain how to leverage disease biology insights to drive development of genomic medicines and discuss the cutting-edge clinical trial […]

12 September 2019

HDRUK to Launch Seven New Data Research Hubs

Health Data Research UK (HDRUK) is launching pioneering data research centres to enable cutting-edge research and innovation to benefit UK patients  Seven new data hubs to be rolled out across the UK to speed up research for new medicines, treatments, and technologies that support quicker diagnoses and save lives  The hubs will use the latest […]

12 September 2019

Bacteria Can Become Resistant Even Without Antibiotic Use

Governments around the world are trying to heavily restrict antibiotic use in the hope that this will prevent the development of resistance which renders many medical treatments useless. However, new research demonstrates that bacterial resistance can spread regardless. Darwin’s theory of evolution tells us that if the selection pressure of antibiotics is applied to a […]

11 September 2019

UK Government Launches World’s Largest Genetics Project to Tackle Deadly Diseases

A new ground-breaking project in the fight against life-threatening illnesses has launched today. The £200 million whole genome sequencing project is being created, forming a partnership of pharmaceutical firms and health experts which will examine and sequence the genetic code of 500,000 volunteers at the UK Biobank, based in Stockport. Prime Minister Boris Johnson said: […]

11 September 2019

Insulin Delivery Drug Could Treat Deadly Brain Cancer

An existing drug used to improve insulin delivery could also be used to treat an aggressive and deadly brain tumour, known as glioblastoma. Glioblastoma (GBM) is a fast-growing tumour that spreads in a web like fashion to infiltrate multiple areas of the brain. As it is not a compact tumour, it is extremely difficult to […]

11 September 2019

Sticky Protein Key to Breast Cancer Metastasis

When cancer cells break off from their initial tumour they can spread throughout the body and invade other organs to form new tumours, in a process known as metastasis. Although metastatic tumours cause 90% of deaths in cancer patients, the underlying mechanisms are not well understood. However, a new study revealed that the expression of […]