Patients with a certain genetic variant have been found to both be more pre-disposed to anxiety and depression and have lower susceptibility to the usual medication. Although anxiety and depression can be developed due to distressing events or stressful periods in a person’s life, there is increasing evidence that some people are more predisposed to […]
NASH is present in nine to 18 million people in America alone. Yet no single drug has yet been approved for its treatment. To discuss why therapies are proving so elusive, and where efforts will be made in the future, FLG has gathered some of the most influential names in the field to discuss the problem in our latest webinar: New Approaches to the Old Hunt for NASH Therapies, held at 4pm on 11 July 2019.
LGBT+ STEM Day – An Interview with Tom Welton, Dean of the Faculty of Natural Sciences at Imperial College London
In honour of LGBT+ STEM day we talked to Professor Tom Welton, Dean of the Faculty of Natural Sciences at Imperial College London and the President-Elect of the Royal Society of Chemistry. He shares his thoughts on diversity and inclusion in the workplace and how attitudes have changed towards LGBT+ people. FLG: What Issues Do […]
A new genetic test has been successfully trialled at a hospital in Oxford to help doctors identify patients most at risk of chemotherapy side-effects. Capecitabine and fluorouracil (5FU) are common chemotherapy drugs for cancers including breast, bowl and stomach. Both drugs act as anti-metabolites and resemble biological molecules found inside cells. When the drug molecules […]
A new CRISPR-based method has managed to eliminate HIV in mice, for the first time potentially curing the lifelong illness of HIV/AIDs. Clinical trials will start next year to identify if the same method could be used to cure humans. HIV is a virus which attacks the immune cells in the body, leaving it […]
Biobank 2019 – An Interview with Anthony Whetton, Professor of Cancer Cell Biology, University of Manchester
The UK Biobank’s 2019 scientific conference concluded this month. We talked to speaker Anthony Whetton, Professor of Cancer Cell Biology at the University of Manchester and Director of the Stoller Biomarker Discovery Centre, about large-scale multi-omic data within UK Biobank.
Fleeting genetic changes observed in stem cells as they differentiate could shed light on the origin of certain genetic diseases. Scientists studying stem cell differentiation usually only compare the differences in gene expression between the fully undifferentiated and differentiated cells. However, new research has revealed that the fleeting genetic changes during cell development could have […]
How DNA is packaged in human fat cells could be the reason why humans became fatter than their closest primate relatives, new research has shown. Whilst the healthy range for human body fat percentage lies between 14% and 31%, other primates have body fat percentages lower than 9%. The genetic reasons behind this difference could […]
Intermountain Healthcare and deCODE Genetics, a subsidiary of Amgen based in Iceland, have announced a major joint collaboration and study of 500,000 genomes centred around discovering new connections between genetics and human diseases. The study represents the largest US DNA-mapping attempt from a single population.
Inscripta has presented its scalable platform for benchtop digital CRISPR engineering, described as world first, at the 2019 Synthetic Biology: Engineering, Evolution & Design (SEED) conference. The technology, “CRISPR-enabled trackable genome engineering” or CREATE, is meant to remove certain limitations of CRISPR to allow for more wide-reaching research in the future.
Scientists at the Technical University of Dortmund have grown a type of tobacco containing 99.7% less nicotine. CRISPR was used to disable certain plant enzymes aiding in nicotine production, potentially creating a tobacco to help users quit smoking.
The last common male ancestor of all humans is far older than previously thought, scientists have found. When the family of Albert Perry, an African-American living in South Carolina, submitted his DNA to commercial genealogy company Family Tree DNA, it was discovered that his Y chromosome was so distinct that his male lineage likely separated from all others around 338,000 years ago.
Biopharma giant Abbvie has announced the acquisition of Allergan for $63 billion in cash and stock. Abbvie said the deal would be “transformational” for both companies, allowing Abbvie to diversify its business while focusing on scientific research and the company’s pipeline.
University of Connecticut scientists have found that both severe epilepsy and breathing irregularities leading to sudden death are linked to the same gene mutation.
From 1 July, international scientists looking to use Chinese genetic material and data must have at least on Chinese collaborator working with them, according to new regulations. This follows a trend as individuals and organisations realise the value of their genetic data.