The largest scale genomic study in Africa has identified a new gene that is linked to the onset of diabetes in African populations. Interestingly, the gene has not been found to be linked to diabetes in European populations. In type 2 diabetes the body is able to produce insulin but the body’s cells do […]
The inaccuracy of a genetic test that gave false positives to patients has resulted in doctors calling for a crackdown on genetic testing. If a woman’s BCRA gene is faulty, her risk of breast and ovarian cancer is much higher than average. People with a family history of these cancers are often tested to identify […]
The Digital DNA series will explore the role of large-scale genetic testing in science, industry and society. We aim to understand both the benefits and risks of this emerging technology and see what the future may hold. In the first of our Digital DNA series, we talked to Dr. Peter Ney, a researcher in the […]
Scientists have genetically engineered neurons in mice to give them hallucinations. The research could help identify why certain people experience hallucinations, associated with several mental illnesses, and inform new treatments. Two genes were inserted into the neuron cells of the mice’s visual cortex, the part of the brain that processes visual information. One coded for […]
Although it has been known that different genes determine different characteristics in male and females, new research suggests that differences in gene expression has a much larger impact than previously thought. Many diseases and traits show difference between the sexes. For example, autism is more common in males than females, but multiple sclerosis is more […]
An evolutionary survival mechanism that helped early humans avoid starvation could be behind the obesity epidemic in society today. Starvation puts considerable stress on cells. The body responds with a mechanism that blocks fat from burning when the body is starving, injured or cold. This enables energy to be conserved so people can survive longer, […]
Researchers have revealed the first vaccine purely designed by artificial intelligence (AI). This has the potential to revolutionise the drug discovery process by making it quicker, cheaper and producing more effective drugs. From target discovery to market, the drug discovery process takes on average nine years and millions of dollars. The majority of this time […]
The UK Biobank’s 2019 scientific conference concluded this month, showcasing fantastic speakers on topics ranging from use of the UK Biobank, to using genomics to understand individual risk. Among them was Professor Josh Denny, Vanderbilt University. FLG spoke to him about his talk on phenome-wide association studies (PheWAS): a research technique used to understand what disease associations can be made with a given gene.
Scientists have found that RNA production is behind the regenerative affects of laser skincare treatments. Laser treatments are a widespread cosmetic procedure to make skin appear younger and healthier. The laser slightly damages the skin cells, forcing them to repair themselves. After the repair process, the skin looks younger, but until recently the mechanism to […]
Epitranscriptomics – An Interview with Samie Jaffrey, Professor of Pharmacology, Weill Cornell Medicine
The study of epitranscriptomics has ramifications for better understanding disease symptoms and pushing forward drug treatment. But it’s also an emerging area still misunderstood by many. FLG spoke to Dr Samie Jaffrey, Professor of Pharmacology, Weill Cornell Medicine, about the field.
A new genetic study has revealed anorexia, previously thought to be solely a psychiatric disease, is influenced by metabolic factors. Anorexia is an eating disorder and a serious mental health condition. Sufferers try to keep their weight as low as possible by eating as little as possible or exercising as much as they can. Sufferers […]
Researchers have developed a new technique to pinpoint immune cells in cancer patients that are reactive against their disease. This research could lead to more targeted immune-based therapies for cancer patients. Immunotherapy is a relatively new field of cancer treatment which works by promoting the patient’s immune system to fight against the cancer. Although immune […]
A study has shown that you can reduce your risk of getting dementia by adapting a healthy lifestyle, regardless of your genetic pre-disposition. Genetic factors can increase a person’s likelihood of getting dementia, but until now it was not known if making lifestyle changes could reduce this risk. 196,383 individuals above 60 years of age […]
A new treatment for malnourished children, using food that promotes a healthy microbiome, has been found to aid recovery better than current alternatives. Malnourished children often struggle to recover and find gaining weight again extremely difficult, even with sufficient food. Scientists have long suspected this is due to the role of the gut microbiome. Gut […]
A gene has been identified in worms that improves their health, but not their lifespan, as they age. Maintaining quality of life is becoming a focus in healthcare for the elderly, as people that live to the same age do not necessarily have the same quality of life. Some maintain both their movement and cognitive […]