A highly conserved mechanism in worms and humans has been discovered by researchers at Monash University that could provide a novel therapeutic approach for neurodegenerative diseases such as Huntington’s and Parkinson’s.
The cause of a rare type of familial epilepsy has been linked to two new gene mutations, as discovered by researchers from the Walter and Eliza Hall Institute. Published back-to-back in Nature Communications, Dr Mark Bennett, Dr Haloom Rafehi and Professor Melanie Bahlo from the Institute made this ground-breaking discovery as part of an international consortium.
New research published in the British Journal of Cancer has identified a link between the so-called “junk DNA” and the risk of developing cancer. Junk DNA refers to regions of DNA that don’t code for proteins but are thought to play in a role in gene expression regulation
Researchers at the Wellcome Sanger Institute uncovered a possible pre-cancerous signature for Wilms’ tumour, a form of kidney cancer mainly affecting children under five years old. Published in Science, the research was the first to compare Wilms’ tumour tissue and healthy kidney tissue to identify any genetic changes that could possibly be predictive of disease progression.
An intriguing (unconventional) study published by the International Journal of Cancer looked at the breast cancer risk in relation to the use of hair dyes and chemical straighteners, after results of previous studies remain inconclusive.
Rory Collins, Principal Investigator and Chief Executive of UK Biobank leads this landmark project. We talk to him about some of the research outcomes from UK Biobank, and why he’s excited to be speaking at the Festival of Genomics this January.
A new research paper has investigated the link between the BAZ1B gene and self-domestication of humans. The same gene has been found to control much of human facial development and be involved in the domestication of dogs and cats, possibly suggesting that humans are self-domesticated.
The analysis of rare genomic copy number variants (CNVs) in siblings of a proband with autism spectrum disorder (ASD) could be used to predict the likelihood of developing ASD themselves, according to an article published today in Nature.
A new wristband has been designed that can suggest the best foods for you to eat according to your DNA profile.
In late 2018, the world was shocked by the news of the birth of the first CRISPR gene edited twin babies. Chinese biophysicist He Jiankui carried out an experiment to create babies with a natural resistance to HIV by editing the CCR5 gene, known to play a role in the immune response.
A new study by Northwestern Medicine has become the first to compare gene expression levels in African American populations by studying the levels of mRNA expressed in the liver. Previous studies have compared only African and European individuals separately and this study aimed to address the “grey” area of mixed ethnicities.
AstraZeneca’s Olaparib has become the first gene-targeted medicine to show benefits in metastatic castration resistant prostate cancer.
The Environmental Determinants of Diabetes in the Young or TEDDY is the largest study of its kind measuring new-borns with an increased risk of Type 1 Diabetes (T1D). The study published in Nature Medicine has uncovered an association between a genetic variant of a pancreatic cell surface-receptor and long-term viral infections.
Researchers at the Centre for Genomic Regulation in Barcelona, Spain have developed a new type of genomics technology that can be used to investigate how species are related to each other, with a possibility of creating new drugs, foods, and materials at a much larger scale than ever before.
A set of research papers suggests that some people need less sleep than others based on a few genetic changes. The papers from the neurology team at the University of California, San Francisco (UCSF) identified three genes that researchers can link to needing less sleep
