The ATDC gene has been identified as necessary for the development of pancreatic cancer. Deleting the gene in pancreatic cells led to “one of the most profound blocks of tumour formation ever observed in a well-known mice model engineered to develop pancreatic ductal adenocarcinoma”.
Two molecules which switch off CRISPR could be used to make gene editing therapies safer in the future. Harvard University’s Amit Choudhary and his colleagues said the molecules could stop CRISPR making unintended changes to DNA, potentially harming the individual.
Genetic research is a big data problem without researchers generally having access to this “big” genomic and medical data. Not only has it been nearly impossible to access enough relevant data to support research, but analysing the data has been slow and challenging due to its sheer volume. To counter this, in recent years a number of pharmaceutical companies have announced large-scale collaborations around genomic data to uncover novel drug targets, validate existing drug pipelines, predict response, and expand therapeutics use. We discuss some of the biggest and most recent.
Out of a whole host of engaging and enjoyable moments at Front Line Genomics’ recent Data Driven Drug Development (D4) conference, held in Boston on 20-21 March, one of the most memorable was definitely the triumph of nQ Medical in our innovation showcase, beating out three other contenders for the claim to be “most innovative” of the technologies on display.
We know it’s hard to believe, but right now there are still some people who haven’t made up their minds to come to the 2019 Festival. Lucky for them we plan for every eventuality, and have prepared the five main reasons everyone should be registering their place at the event right now.
The Festival has really captured the imagination of leading scientists – particularly in the UK. So much so, that increasingly we are lucky to attract incredible speakers who hugely enrich the experience of our attendees. This year is stronger than ever. We luckily got a chance to visit some of our top speakers before the […]
With just under two weeks till the festival, it’s time to start thinking logistics. The more scatter-brained of our readers needn’t worry, however: we’ve got everything you need covered in this handy guide, whether it’s things to remember before you arrive at the festival, the best things to do once there and the last couple of things to remember when it’s all done.
The Science and Science Careers’ 2018 annual Top Employers Survey polled employees in the biotechnology, biopharmaceutical, pharmaceutical, and related industries to determine the 20 best employers in these industries as well as their driving characteristics.
Researchers at the Stanford University School of Medicine and their collaborators at other institutions have identified a link between how proteins bind to our DNA and how cancer develops.
Genome Sequencing Found Feasible and Informative for Pediatric Cancer Treatment Findings Reported at ASHG 2018 Annual Meeting
Presenting author Scott Newman, PhD; Jinghui Zhang, PhD; and Kim Nichols, MD, along with an interdisciplinary team at St. Jude Children’s Research Hospital, studied 253 pediatric oncology patients with a variety of cancers.
Researchers Describe Asthma’s Effects on Airways at the Single Cell Level Findings Reported at ASHG 2018 Annual Meeting
By sequencing genetic material at a cell-by-cell level, researchers have described how type 2-high asthma affects the airways and results in mucus production with more detail than ever before.
Genomics England names Congenica as its Clinical Decision Support Service partner for the delivery of the NHS Genomic Medicine Service.
Pioneering Survey of Clinical NGS QC Practices Proves Need for Purpose-Built QC Solutions to Standardise Industry
The QC Survey, Conducted by SeraCare and GenomeWeb, Highlights Industry-Wide Variability of Testing Methods and Results
Zika virus may be sexually transmissible for a shorter period than previously estimated, according to a new systematic review.
New video shows how pieces of DNA once thought to be useless can act as on-off switches for genes.