Solution Enables Clinical Labs to Quickly Convert Genomic Insights to Targeted Therapies
This week at the Association for Molecular Pathology (AMP), Fabric Genomics will announce its expanded somatic cancer solution which provides seamless genomic analysis and clinical reporting to clinical labs. The offering enables therapy matching for cancer patients, giving clinicians targeted treatment choices for cancer patients. Now clinical labs have one integrated platform for the interpretation of somatic cancer panels, hereditary panels, and whole genomes.
“The Fabric Genomics’ somatic cancer solution is a natural extension of our already established platform for hereditary diseases and furthers Fabric Genomics’ goal to improve cancer clinical care through genomic medicine,” said Paul R. Billings, M.D., Ph.D., Chief Medical Officer at Fabric Genomics. “Being able to quickly interpret somatic cancer variants from a tumor or liquid biopsy, and then match those to targeted therapies, is of critical importance to successfully treating cancer patients. NGS-based cancer panels are increasingly being used by clinicians to match cancer patients with FDA-approved drugs and experimental therapies, and improve patient outcomes.”
Fabric Genomics’ cancer solutions provide a next generation sequencing workflow for both inherited cancer risk and somatic cancer testing, including solid-tumor, hematology, and liquid biopsy samples. The company’s expanded somatic cancer capabilities now include variant calling, annotation from cancer-specific databases, clinical curation from multiple providers, and the ability to quickly create physician-ready clinical reports. Somatic variants can be scored and reported in accordance with the 2017 AMP scoring guidelines, which were created to provide a standardized format for presenting somatic variants in a clinical report. The clinical reports generated with Fabric Genomics’ somatic cancer offering are already being used in tumor board meetings at clinical sites. The expanded somatic cancer offering adds to Fabric Genomics’ already established analysis platform for hereditary diseases, as demonstrated by partnerships with Genomics England, Rady Children’s Institute for Genomic Medicine, and The Utah Genome Project.
“Fabric Genomics is a leader in genomic analysis of hereditary diseases, focusing on helping critically-ill children in the NICU/PICU, children with rare diseases, and patients who carry a hereditary mutation that puts them at risk for diseases such as cancer, cardiovascular disease, Alzheimer’s Disease, and more,” said Dr. Joshua Schiffman, M.D., Professor of Pediatrics at the University of Utah, Medical Director of the Family Cancer Assessment Clinic at Huntsman Cancer Institute, and Fabric Genomics’ Scientific Advisory Board Member. “We need the highest scientific rigor and clinical validation to drive the adoption of clinical genomics in cancer
risk and surveillance.”
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