VirION: Towards Long-Read Viral Metagenomics
Viruses are the most abundant organisms in the ocean and grease the wheels of global carbon biogeochemistry. Recently, our understanding of viral ecology has taken a major leap forward with the use of viral metagenomics. However, short-read sequencing used for this purpose has its drawbacks — many of the most abundant and important viral taxa fail to assemble and are thus lost from studies.
On this webinar, Ben Temperton, expert lecturer on Bioinformatics at The University of Exeter, will present new methods for using Oxford Nanopore Technology’s MinION for long-read viral metagenomics. He will show how these new methods dramatically increase viral diversity captured in marine samples, and provide insight into host-virus interactions in a way that cannot be achieved with short-read technology.
He will be sharing his bioinformatic pipelines to improve sequence fidelity, and discussing how MinION technology is bringing scientists closer to high-throughput single-virus genomics from environmental samples.
When: Tuesday, July 10th, 2018
Time: 8:00am PDT/ 11:00am EDT/ 4:00pm BST
The webinar will be available on-demand after this date.
Ben Temperton spent 7 years as a professional software engineer before retraining as a marine microbiologist, gaining his PhD from Queens University Belfast. He spent two years as a postdoctoral scholar at Oregon State University with Prof. Steve Giovannoni using metagenomics and metaproteomics to understand the role of the SAR11 clade in global marine carbon biogeochemistry. During this time, he identified four new viruses infecting SAR11 as the most abundant viruses on Earth. Upon his return to the UK, he established the first UK environmental Single Cell Genomics Laboratory at Plymouth Marine Laboratory, before moving to the University of Exeter to set up his own research group studying marine viral ecology and the global impact of predator-prey interactions on carbon remineralisation.