CRISPR-Cas9 can carry out precise genome editing even without the assistance of donor DNA templates, a team of scientists from Brigham and Women’s Hospital and the Broad Institute of MIT and Harvard have found.
The editing of muscle cells in young beagles, bred to Duchenne muscular dystrophy, to remove a key barrier to higher protein production could greatly further the treatment of the disease in humans.
A new scientific innovation is set to help scientists understand the causes of cancer with greater speed and precision than ever before. Rather than looking at individual gene mutations on their own, scientists can now create models incorporating a number of mutations.
For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.
Researchers at the Key Laboratory of Synthetic Biology in Shanghai have used CRISPR to create a new species of yeast that only has a single giant chromosome.
To find out which DNA repair enzymes are critical to homology-directed repair after CRISPR cutting, researchers have knocked out, one at a time, more than 2,000 genes known or suspected to be involved in DNA repair, a function critical to a healthy cell.
Two new research studies have identified a method by which bacteriophages can cooperate in order to infect bacterial cells with CRISPR defence mechanisms.
A new study has found that the Cas9 gene editing scissors don’t stop cutting after we tell them to. Can we use different scissors?
Scientists have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought.
The Nuffield Council on Bioethics has concluded that using gene editing tools on human embryos, sperm, or eggs for heritable gene editing could be ‘morally permissible’ in some cases.
Researchers have demonstrated a novel gene editing approach using electrical fields that could greatly reduce the time it takes to precisely edit DNA in cells.
Scientists are taking advantage of the “self-homing” abilities of cancer cells and are creating armies of cancer-killing cells using CRISPR gene-editing.
The CRISPR genome editing method has been delivered directly in human sperm cells giving hope that correcting mutations in human sperm cells is possible and may lead to the prevention of disease being passed on by fathers.
Biochemists have discovered the cause of genome editing failures with the ‘hyped’ CRISPR system, and how the process can be made to be much more efficient.
Researchers have for the first time, used gene-editing tools in adult monkeys to disable a gene throughout much of the liver.
