For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.
Researchers at the Key Laboratory of Synthetic Biology in Shanghai have used CRISPR to create a new species of yeast that only has a single giant chromosome.
To find out which DNA repair enzymes are critical to homology-directed repair after CRISPR cutting, researchers have knocked out, one at a time, more than 2,000 genes known or suspected to be involved in DNA repair, a function critical to a healthy cell.
Scientists have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought.
The Nuffield Council on Bioethics has concluded that using gene editing tools on human embryos, sperm, or eggs for heritable gene editing could be ‘morally permissible’ in some cases.
Scientists are taking advantage of the “self-homing” abilities of cancer cells and are creating armies of cancer-killing cells using CRISPR gene-editing.
Researchers have for the first time, used gene-editing tools in adult monkeys to disable a gene throughout much of the liver.
Researchers have for the first time succeeded in converting human skin cells into pluripotent stem cells by activating the cell’s own genes, using gene editing technology CRISPRa.
CRISPR gene drives have been tested in laboratory mice for the first time, offering a way in which multiple genes in mice can be altered to model complex multigenic human diseases. Could this step eventually lead to the eradication of pest species or is the technology still too controversial?
Researchers in the UK have invented a switch that allows them to turn protein expression off and on at will, potentially offering a control over gene editing tools.