A U.S. start-up has entered the race to commercialise CRISPR. By using “base editing,” the company hope to treat some of the most devastating genetic disorders.
A bit of advice for any criminals inspired to try and edit their own genes – it’s unlikely to work, and it may present health risks.
There are fears that CRISPR could be used by criminals to clear their names from forensic databases or evade detection, as access to the technique becomes more widely available.
Researchers at the Broad Institute of MIT and Harvard have reported that their platform, SHERLOCK, now can be used to detect viruses directly in clinical samples such as blood or saliva.
Biomedical engineers have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment.
Researchers have been developing CRISPR gene editing as a potential therapeutic tool for years, but now they have turned their attention to using it in cancer diagnostics.
Researchers have discovered a way to greatly improve the accuracy of gene-editing technology by replacing the natural guide molecule it uses with a synthetic one called a bridged nucleic acid, or BNA.
Studies using CRISPR on monkeys look encouraging, but more needs to be done before the gene-editing technology can be used on humans.
The team who previously stated that CRISPR caused hundreds of unintended mutations are unable to replicate their controversial result.
Scientists have created a new tool that targets not DNA, but RNA, and used it to correct a protein imbalance in cells from a dementia patient, restoring them to healthy levels.
The fragile X syndrome is the most common form of intellectual impairment in men, affecting 1 out of 3,600 boys. Scientists have used CRISPR to restore its activity.