Data

Data is at the heart of applicable genomics. As the volume and depth of genomic data grows, bioinformaticians are translating the data into interpretable patterns leading to new biological insight.

Digital DNA: How DNA Testing is Being Used to Cheat the System

The Digital DNA series explores the role of large-scale genetic testing in science, industry and society. We aim to understand both the benefits and risks of this emerging technology and see what the future may hold. When Ralph Taylor registered his new business, he attempted to declare it as a disadvantaged business enterprise. Businesses headed […]

Digital DNA: Hacking DNA Databases – An Interview with Peter Ney

The Digital DNA series will explore the role of large-scale genetic testing in science, industry and society. We aim to understand both the benefits and risks of this emerging technology and see what the future may hold. In the first of our Digital DNA series, we talked to Dr. Peter Ney, a researcher in the […]

Chinese Rules on Global Use of Genetic Material Come into Effect

From 1 July, international scientists looking to use Chinese genetic material and data must have at least on Chinese collaborator working with them, according to new regulations. This follows a trend as individuals and organisations realise the value of their genetic data.

A Guide to Biodata: Analysis, Integration and Management

It has now been 16 years since the Human Genome Project sequenced the first ever human genome: in that time, as has been mentioned in previous editions of this report, more than 500,000 genomes have been sequenced, generating enough data to drastically raise computational resource usage and create a need for rapid innovation to offset […]

Molecules Discovered to Better Control CRISPR Edits

Two molecules which switch off CRISPR could be used to make gene editing therapies safer in the future. Harvard University’s Amit Choudhary and his colleagues said the molecules could stop CRISPR making unintended changes to DNA, potentially harming the individual.

The Rise of Population-scale Genomic Projects for Pharma R&D Investments

Genetic research is a big data problem without researchers generally having access to this “big” genomic and medical data. Not only has it been nearly impossible to access enough relevant data to support research, but analysing the data has been slow and challenging due to its sheer volume. To counter this, in recent years a number of pharmaceutical companies have announced large-scale collaborations around genomic data to uncover novel drug targets, validate existing drug pipelines, predict response, and expand therapeutics use. We discuss some of the biggest and most recent.

The One-Stop Guide to Genomic Data, Courtesy of Front Line Genomics

Front Line Genomics’ “Biodata Analysis and Management – Genome Analytics, Interoperability, and Data Life Cycle” report isn’t just an update of our old Genomic Data 101 guides: packed with new information on AI and machine learning,. data discoverability and data interoperability, it is much much more.

DNA Mutation “Fingerprint Database” Identifies Cancer Causes

Cambridge and London researchers have created a database of DNA mutation “fingerprints” which can be used to determine the environmental factors contributing to a patient’s tumour. The study, published in Cell journal, can determine 41 different environmental agents linked to cancer, including the traces left in lung tumours by chemicals linked particularly to tobacco smoke.