Diagnostics

Diagnostics allow for the identification of cancer types and other crucial biomarkers, and are used right through from discovery to market.

Brain Imaging Reveals Networks Linked to Increased Suicide Risk

Brain networks associated with suicide have been identified by examining brain images from the past two decades. The study published in Molecular Psychiatry found changes in the prefrontal cortex were important risk factors in suicidal thoughts and behaviours. 800,000 people die globally by suicide every year – one every 40 seconds. It is the second […]

Changes in Gut Microbiota Implicated in Colorectal Cancer

Gut microbiota has wide reaching effects on health and disease. A study published in Proceedings of the National Academy of Sciences, PNAS, has demonstrated that gut imbalance promotes the onset of colorectal cancer, going on to invent a blood test to identify the epigenetic signatures.

New Technique to Identify Genes Causing Rare Diseases

A new data analysis technique has shown success in identifying the faulty genes that cause rare genetic diseases. A Struggle for Diagnosis Despite advances in sequencing technologies, rare disease patients still struggle to receive a diagnosis. Only 30% of patients receive a diagnosis after whole genome sequencing, which is often used as a last resort […]

New Blood Test Can Detect Multiple Types of Cancer

A new blood test has been shown to identify different cancer types with a high degree of accuracy. When cancer cells die, they shed their DNA into the blood. Previous diagnostic tests work by identifying the genetic mutations present in the cancer cell DNA. However, this technique is limited in its ability to distinguish where […]

Using AI to Discover Dark Matter DNA – An Interview with Laxmi Parida, IBM

We talked to Laxmi Parida, Fellow and Computational Genomics Research Lead at IBM, to discuss her recent ground-breaking research paper on an AI algorithm that can distinguish blood cancer subtypes from dark matter DNA. Personalised Medicine for Cancer Patients The future of personalised medicine relies on quick and non-invasive diagnostics. Simple blood tests for tumour […]

Breathalyser Test Can Predict Which Patients Will Respond to Lung Cancer Immunotherapy

A newly developed ‘electronic nose’ can measure chemicals in the breath of small cancer lung patients to determine if they will respond to immunotherapy treatment. Immunotherapy is Changing Cancer Care Immunotherapy treatments harness the body’s immune system to fight the cancer cells, which is transforming the treatment of advanced stage cancers. However, only a small […]

Genomics Medicine Ireland Announces Strategic Advisory Board

Genomics Medicine Ireland (GMI) has announced the establishment of a Strategic Advisory Board that will work collaboratively with GMI in shaping the company’s strategy for the application of large-scale genomics population studies on the island of Ireland, in addition to providing input and advice on the multi-disciplinary integration of genomics into the Irish healthcare system. […]

New Blood Test Can Predict Cancer Progression

A new technique to analyse the tumour DNA present in patient’s blood circulations is an effective method to monitor breast cancer progression. The technique has been shown to give a hundred-fold improvement in the detection limit for tumour DNA. Analysis of the DNA that the tumour sheds into the bloodstream provides a non-invasive means of […]

Colour Changing Tattoos Can Sense Biomarkers

Scientists have developed tattoos that change colour depending on the interstitial fluid concentration of key biomarkers. The development is a step towards developing quicker diagnostics. The biomarkers studied were pH, glucose and albumin. Variation of blood pH can be indictive of a range of health conditions and glucose sensing is extremely useful for monitoring diabetes. […]

Changes to Genetic Risk Factors Not Always Reported to Patients

Patients are not being informed about changes to their genetic risk factors for cancer, a new study shows. If an individual has a family history of a type of cancer, they can get a genetic test to identify their own cancer risk. Identifying a genetic risk means that person can get regular check-ups and be […]

Following the Recent Raid, Could uBiome Become Theranos 2.0?

uBiome, a Silicon Valley startup providing tests focussing on the microbiome and its importance to health, is under investigation after an FBI raid on its offices over how it was allegedly billing its customers. The company has received significant criticism recently for handling of the cofounders’ relationship and alleged corner-cutting during its scientific work.

ClinGen Gets FDA Recognition

The US Food and Drug Administration (FDA) announced ClinGen as the first FDA-designated public genetic variants repository this week.