A new blood test has been shown to identify different cancer types with a high degree of accuracy. When cancer cells die, they shed their DNA into the blood. Previous diagnostic tests work by identifying the genetic mutations present in the cancer cell DNA. However, this technique is limited in its ability to distinguish where […]
The study of non genetic heritability. Epigenetics can have an incredible phenotypic effect, and the study of epigenetic factors and mechanisms is an exciting and developing field.
Changing Attitudes to Cannabis Cannabis is now legalised for recreational use in 11 US states and attitudes around its risk are changing rapidly. Between 2002 and 2014, the percentage of adults in the US who perceived cannabis use as risky declined from 50% to 33%. However, as cannabis usage becomes more widespread the health risks […]
A gene that codes for a telomere protein is the key to regulating stem cell pluripotency, new research shows. Pluripotent stem cells have the ability to differentiate into any type of specialised cell in the body. They hold huge potential for a range of regenerative medical treatments. Scientists have previously struggled to understand the genetic […]
An Alzheimer’s drug that is used to slow cognitive decline can reverse the brain damage caused by teenage drinking, shows a new rat-based study. Adolescent brains are more susceptible to alcohol damage than adult brains. Excessive teenage drinking reduces the formation of neurons in the hippocampus which impairs learning and memory. The damage can also […]
The myth of the goldfish’s three second memory has long prevailed in popular culture. However, new research has suggested that unlike humans, fish are able to conserve memories over generations using epigenetic mechanisms. Epigenetic modifications can change the expression of DNA without changing the DNA code itself. Often this is in the form of DNA […]
Epitranscriptomics – An Interview with Samie Jaffrey, Professor of Pharmacology, Weill Cornell Medicine
The study of epitranscriptomics has ramifications for better understanding disease symptoms and pushing forward drug treatment. But it’s also an emerging area still misunderstood by many. FLG spoke to Dr Samie Jaffrey, Professor of Pharmacology, Weill Cornell Medicine, about the field.
New research has explored the dynamic genetic changes taking place during the bluehead wrasse’s sex change. The bluehead wrasse social group consists of one dominant blue male fish and a harem of yellow females. However, when the dominant male is removed from the group the largest female immediately undergoes a full sex change and becomes […]
A study conducted by Northwestern University researchers has found that long-term poverty can be “embedded” across the genome. Lower socioeconomic status was found to be associated with levels of DNA methylation, a key epigenetic mark that can influence expression, across more than 1,500 genes.
Cancer scientists led by principal investigator Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have combined “liquid biopsy,” epigenetic alterations and machine learning to develop a blood test to detect and classify cancer at its earliest stages.
By identifying and characterizing specific types of mutations in individual cell lines, using a combination of whole genome sequencing and multi-omic approaches, researchers hope to improve stem cells’ therapeutic uses and potential.
New video shows how pieces of DNA once thought to be useless can act as on-off switches for genes.
Scientists have mapped 41 genes that increase the risk of developing hay fever, in a new study of almost 900,000 people. Of the genes, 20 are new to science.
Scientists have gained a glimpse of how marks on our genes that could be linked to adverse health outcomes in later life behave in the first few days after conception.