A modified version of CRISPR has been used to reverse genetic obesity in two different mouse models without editing any genes. The technique uses the guidance system in CRISPR to target certain genetic sequences and amplifies existing gene activity to ramp up protein production.
Scientists from the University of Pennsylvania have created a test using gene-editing tools such as CRISPR to identify a gene variant responsible for severe hypertrophic cardiomyopathy (SHC). SHC is an often-familial disease which thickens heart walls and is linked to a variant in the TNNT2 gene.
The body is naturally geared to assimilate energy from the food we eat and store it as fat until it is needed. But now, researchers have managed to inhibit the body’s ability to store fat.
Keeping fit, even if you’re born with a high genetic risk for heart disease, still works to keep your heart healthy, according to a new study.
Being obese or having a higher BMI while carrying a BRCA mutation is positively linked with higher levels of damage to the DNA in normal breast gland cells, new research suggests.
New study brings new insights into the correlation of physical activity and dietary habits with weight gain in people who carry different variations of the FTO gene—aka ‘the fat gene.’
The World Anti-Doping Agency has considered obtaining Olympic athletes’ genetic code for years, and now that could soon be becoming a reality, thanks to the decreasing cost of sequencing.
Periods of skeletal muscle growth are ‘remembered’ by the genes in the muscle, helping them to grow larger later in life.
Consumption of dietary fibre can prevent obesity, metabolic syndrome and adverse changes in the intestine by promoting growth of “good” bacteria in the colon.
New research suggests that an enzyme called SNRK suppresses inflammation in obesity-related “white fat” while increasing metabolism in heat-producing “brown fat.”