CRISPR-Cas9 can carry out precise genome editing even without the assistance of donor DNA templates, a team of scientists from Brigham and Women’s Hospital and the Broad Institute of MIT and Harvard have found.
Maize is one of the most economically important crops globally and much effort has been spent generating the high quality B73 reference genome. However, the 10 chromosome, 2.3 gigabase (Gb) B73 reference genome was a substantial challenge due to the fact it is comprised of 85% transposable elements, 75% of which are long terminal […]
Prenatal gene therapy has been used to prevent acute neuronopathic Gaucher’s disease, however this approach is using viruses to deliver normal copies of genes.
Researchers have demonstrated a novel gene editing approach using electrical fields that could greatly reduce the time it takes to precisely edit DNA in cells.
Scientists are taking advantage of the “self-homing” abilities of cancer cells and are creating armies of cancer-killing cells using CRISPR gene-editing.
The CRISPR genome editing method has been delivered directly in human sperm cells giving hope that correcting mutations in human sperm cells is possible and may lead to the prevention of disease being passed on by fathers.
A single administration of a therapeutic vector in mouse models cures type 2 diabetes and obesity in the absence of long-term side effects, researchers report.
New research links higher body fat with lower breast cancer risk before menopause.
Researchers have discovered that genes located in a large chromosomal aberration associated with autism interact with each other to modulate the variable symptoms of the disease.
The concept of three-parent babies defies what we learned in health class. But how and when is the third parent involved? At what stage? Jennifer Barfield gives us an update on the birds and the bees.
Researchers at King’s College London have shown that rats with spinal cord injuries can re-learn skilled hand movements after being treated with a gene therapy.
Shares in various companies using gene editing technologies fell earlier this week, after it was widely reported that CRISPR may raise the risk of cancer in edited cell populations.
Using genome-wide genetic approaches, researchers systematically screened for the loss of an additional gene that could rescue a genetic disease, and found it.
FDA commissioner, Scott Gottlieb said that he expects the FDA to approve 40 gene therapies by 2022 in a fireside chat at the 2018 BIO International Convention.
Singapore could become the second country to legalise MRT but they are considering a new method that differs from the two currently legal in the UK.
