Determining Treatment Relapse at Diagnosis in Children with ALL
Researchers have developed a technique that allowed them to determine at diagnosis whether children with acute lymphoblastic leukaemia would relapse following treatment.
Gene Therapy
Gene-Therapy Trials for Inherited Form of Blindness Could Start Soon
Researchers have developed a gene therapy that successfully treats a form of macular degeneration in a canine model. Following safety studies, a human clinical trial could be less than two years away.
Erasing Side Effects of Promising Cell-Based Cancer Therapy
Scientists created an odd couple: a modified version of an immune-signalling protein and a coordinately modified receptor for this protein. The two bind only to each other, easing an advanced anti-cancer therapy’s side effects.
Engineered T-Cells Hunting and Attacking Brain Tumours
Genetically engineered cancer-killing T-cells can hunt and attack brain tumours that display a new molecular target that is highly prevalent on brain cancer cells, report researchers
Sandhoff Disease Study Shows Proof of Principle for Gene Therapy
Babies with the deadly genetic disorder Sandhoff disease begin to miss developmental milestones months after birth, but new research describes step towards gene therapy to help.
Precision Cancer Therapy Shows Early Signs of Success
Patients with a variety of advanced cancers occurring in different sites of the body have trialed a larotrectinib, with three-quarters of patients, both adults, and children responding to the drug.
Light-Activated Drugs Could Kill Cancer with Fewer Side Effects
Light-activated cancer drugs that don’t cause the toxic side effects of current chemotherapy treatments are closer to becoming a reality, a new study suggests.
Oxford BioMedica Gains Ground With Latest Gene Therapy Contract
Britain’s Oxford BioMedica has a lot to be happy about right now, since its win in a second $100 million contract to supply gene therapy material from Bioverativ.
Better Way Into Brain Could Cut Gene Therapy Side Effects
Researchers have found a structure on the small viruses that deliver gene therapy that makes them better at crossing from the bloodstream into the brain.
Targeting Tumours Before They Metastasize
New research from The Scripps Research Institute may give scientists a chance to target tumours before they metastasize.
Cancer Stem Cells that Drive Triple-Negative Breast Cancer
Researchers have identified a new stem cell pathway that allows a highly aggressive form of breast cancer—triple-negative breast cancer—to thrive.
Researchers Turn Off Multi-Drug Resistance Capabilities in Cancer Cells
New findings point to a technique that uses specially designed nanoparticles and near-infrared laser treatment to cause cancer cells to lose their multidrug resistance capabilities for days at a time.
We Can Now Read the Whole Genome of a Fetus in the Womb
Reading the whole genetic blueprint of a fetus long before birth could become a routine procedure thanks to a new blood test.
New System to Match Patients’ Genetic Markers with Cancer Drugs
Scientists have developed a new system to rapidly determine which cancer drugs are likely to work best given a patient’s genetic markers.
CRISPR to Target Leukaemia
Researchers used CRISPR gene-editing to equip certain immune cells with a homing beacon to target leukaemia.
