New research has indicated that a species’ lifespan can be predicted by the rate of telomere shortening but not by the initial telomere length, as previously thought. Telomeres are repetitive sequences of DNA nucleotides found at the end of chromosomes. They protect the chromosome from degradation during cell division. As species age, the length of […]
Researchers have identified the genetic changes that cause corals to bleach when ocean temperatures increase. This insight gives researchers the possibility to genetically engineer corals to make them more resistant to bleaching. At normal temperatures, corals form a symbiotic relationship with microalgae, known as dinoflagellates. The algae provide their photosynthetic products to the coral so […]
A variant of the common cold virus has shown promising trial results as a treatment for bladder cancer. Bladder cancer is the tenth highest incident cancer in the UK and kills approximately 5,300 people a year. Current treatments for bladder cancer mostly have high recurrence rates or dangerous side-effects. 15 non-muscle invasive bladder cancer patients […]
Researchers have found a weakness in software used for genomics data storage, which could leave patients’ information vulnerable to cyber-attacks. The increasing speed and availability of genetic sequencing technologies has enabled personalised medicine to make significant progress over the last few years. Patient’s genetic profiles are considered when choosing chemotherapy treatment and cures are being […]
Patients with a certain genetic variant have been found to both be more pre-disposed to anxiety and depression and have lower susceptibility to the usual medication. Although anxiety and depression can be developed due to distressing events or stressful periods in a person’s life, there is increasing evidence that some people are more predisposed to […]
A new genetic test has been successfully trialled at a hospital in Oxford to help doctors identify patients most at risk of chemotherapy side-effects. Capecitabine and fluorouracil (5FU) are common chemotherapy drugs for cancers including breast, bowl and stomach. Both drugs act as anti-metabolites and resemble biological molecules found inside cells. When the drug molecules […]
Biobank 2019 – An Interview with Anthony Whetton, Professor of Cancer Cell Biology, University of Manchester
The UK Biobank’s 2019 scientific conference concluded this month. We talked to speaker Anthony Whetton, Professor of Cancer Cell Biology at the University of Manchester and Director of the Stoller Biomarker Discovery Centre, about large-scale multi-omic data within UK Biobank.
Fleeting genetic changes observed in stem cells as they differentiate could shed light on the origin of certain genetic diseases. Scientists studying stem cell differentiation usually only compare the differences in gene expression between the fully undifferentiated and differentiated cells. However, new research has revealed that the fleeting genetic changes during cell development could have […]
How DNA is packaged in human fat cells could be the reason why humans became fatter than their closest primate relatives, new research has shown. Whilst the healthy range for human body fat percentage lies between 14% and 31%, other primates have body fat percentages lower than 9%. The genetic reasons behind this difference could […]
Intermountain Healthcare and deCODE Genetics, a subsidiary of Amgen based in Iceland, have announced a major joint collaboration and study of 500,000 genomes centred around discovering new connections between genetics and human diseases. The study represents the largest US DNA-mapping attempt from a single population.
Inscripta has presented its scalable platform for benchtop digital CRISPR engineering, described as world first, at the 2019 Synthetic Biology: Engineering, Evolution & Design (SEED) conference. The technology, “CRISPR-enabled trackable genome engineering” or CREATE, is meant to remove certain limitations of CRISPR to allow for more wide-reaching research in the future.
The last common male ancestor of all humans is far older than previously thought, scientists have found. When the family of Albert Perry, an African-American living in South Carolina, submitted his DNA to commercial genealogy company Family Tree DNA, it was discovered that his Y chromosome was so distinct that his male lineage likely separated from all others around 338,000 years ago.
The amount of data captured by pharma companies today is fast outpacing best use for it. The ever-evolving scope of the field also means that many senior-level professionals do not fully understand the importance of getting data right in their business, or missing a potential opportunity that their rivals seize. Stemming from Front Line Genomics’ […]
From 1 July, international scientists looking to use Chinese genetic material and data must have at least on Chinese collaborator working with them, according to new regulations. This follows a trend as individuals and organisations realise the value of their genetic data.
Consumer genomics company Ancestry has launched the new upgrade to its AncestryDNA experience, Ancestry Communities. Contrary to many commercial DNA sites, Communities promises to specify UK users’ genetic ancestry to a county level.