Researchers from the Wellcome Sanger Institute have just released the first high-quality Eurasian Otter (Lutra lutra) genome in partnership with the Cardiff University Otter project, aiming to support the study of their biology and support conservation efforts.
FLG: Could you give us an introduction of yourself and the work you do? I’m Luigi Grassi and I’m an Informatics Scientist at AstraZeneca. I’m responsible for designing and performing bioinformatical analyses of the high throughput sequencing experiments we use to characterise stable cell lines expressing biotherapeutics. FLG: What motivated you to pursue a career […]
Even on Valentine’s Day the snoring of a sleeping companion, can be a hard habit to excuse. And, while a UK Biobank analysis may not help to silence-the-snooze of your significant other, the insights published today are interesting, nonetheless. The observational and genetic study of 400,000 snoring and non-snoring participants using data from the UK […]
“We are all Billionaires in Terms of our Genome Data” – Interview with Prof. Ernst Hafen, Professor of Systems Genetics, ETH Zurich
Professor Ernst Hafen is based at the Institute of Molecular Systems Biology at ETH Zurich. He studied the developmental and cell biology of fruit flies for over 30 years and now focuses on human genomic data and what it can do for health research. FLG: Could you give us an introduction of yourself and the […]
“We Are Starting to Appreciate Non-Coding DNA” – Interview with Dr Sandra Smieszek, Vanda Pharmaceuticals Inc.
Dr. Sandra Smieszek is the Head of Genetics at Vanda Pharmaceuticals Inc. She trained at the Institute for Computational Biology and has extensive experience in several aspects of human genetic studies including case control studies from clinical sequencing, whole genome explorative analyses, reverse phenotyping enabling precision medicine and pharmacogenomics.
In early December, an outbreak of respiratory illness was reported in Wuhan, China. Scientists quickly determined the sickness was caused by a new virus from the coronavirus family. In an attempt to limit the spread of the virus, China has reacted with transportation lockdowns and public health advisories.
The biomolecular code of the deadly Wuhan pneumonia virus, the coronavirus, is now available to view on the UCSC Genome Browser. With nearly 41,000 cases and 910 deaths to date, the deadly virus has forced more than 50 million people to be quarantined by the Chinese government in an aim to stop the spread of the virus.
Foundations for AI are “Critical” to our Continued Success – Interview with Dr Paul Agapow, AstraZeneca
Dr Paul Agapow is a Health Informatics Director at AstraZeneca where he explores the possibilities of biomedical Big Data and its application to personalised medicine and therapies, in particular using novel algorithms and machine learning in discovering patient subtypes and predicting outcomes.
New research has identified mutations that could lead to the lengthening of telomeres, a hallmark of cancer cells and an important focus in developing targeted treatments. Scientists from the German Cancer Research Center looked at cancer cells to find the ways some of them achieve immortality in a study as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG).
New research from institutions in Singapore and China has identified genetic differences that occur between lung adenocarcinomas in East Asians and Europeans. Published in Nature Genetics, the researchers found that lung adenocarcinomas had more stable genomes in East Asians than in Europeans, and a stronger difference in smokers compared to non-smokers.
Gene variants that could play a role in the incongruence transgender individuals experience may have been found in the genes for oestrogen receptor pathways. Published in Nature, this study identified some of the first biological evidence that linked 21 gene variants in 19 genes with a possible role in sex-specific development during birth in an […]
The study of four children – two of whom were buried approximately 8,000 years ago and two 3,000 years ago – from Shum Laka, Cameroon has revealed new insights into how Africa was populated.
Interview with Dr Halima Moncrieffe, Assistant Professor, Cincinnati Children’s Hospital Medical Center
Dr Halima Moncrieffe is an Assistant Professor at Cincinnati Children’s Hospital, ranked top 3 in the USA, where she combines genomics with immunology to understand medication response and disease etiology. Halima is an award-winning immunologist who’s ultimate goal is to move towards a cure for Juvenile Idiopathic Arthritis, so children can live pain-free and to their full potential
Dr Michelle Krishnan is the Translational Medicine Leading in Rare Diseases at Roche where she focuses on developing transformative therapies for rare neurodevelopmental disorders to deliver meaningful benefit for patients and families, and is responsible for the clinical development of programmes from early research to clinical trials.
We’ve just completed our 5th Annual Festival of Genomics, which was an incredible experience. Almost 2,000 people came through the doors to see 120 speakers, 50+ exhibitors, 5 theatres of talks and so much more. Thank you to all who attended and made this festival the success it was. We hope you all had a fantastic […]