Genetics

George Church Robustly Defends his “DNA Dating App”

George Church of Harvard University has been under heavy scrutiny after news broke out of a new “DNA Dating App” he has been involved in developing, during a recent interview with 60 minutes. The news has led to a significant backlash from some quarters, including from some within the genomics community, that the app is unethical and represents a form of eugenics.

Peanut Allergy Severity – Blame the Genome

Novel genes associated with the peanut allergy severity and the way the genes interact together have been identified by researchers at the Icahn School of Medicine at Mount Sinai. The findings from this study could lead to the development of better treatments and approaches to identify biomarkers that can predict the severity of a peanut allergy before exposure.

Chemotherapy Resistance Could be Due to Mitochondrial Stress

Researchers at the Salk institute have discovered a way in which some cancers resist chemotherapy. Published in Nature Metabolism, they showed that mitochondria can signal to the rest of the cell when there is stress or chemicals that can damage DNA, such as chemotherapy.

The Saliva Test to Detect Mouth and Throat Cancer

A new non-invasive method to detect the presence of human papilloma virus (HPV)-16 in saliva has been successfully used in a collaboration between Duke University, UCLA, and University of Birmingham. HPV-16 is a high-risk virus known to be an etiologic agent for the development of head and neck cancers, specifically with oropharyngeal caners (OPCs).

Over 100 Variants Found to Influence Psychiatric Disorders

Scientists at Massachusetts General Hospital (MGH) and the Psychiatric Genomics Consortium have discovered that many distinct psychiatric diseases share a common genetic basis. More than 100 genetic variants were found to play a role in determining risk levels for different mental health conditions.

Blame Double XX for Autoimmune Issues

Researchers from the University of California Los Angeles (UCLA) have discovered a possible explanation for why autoimmune disease are more common in females. The research based on mouse models showed that the extra X chromosome in females may be to blame.

Deep Learning Technology Used to Decode Gene Interactions

Computer scientists at the Carnegie Mellon University in Pittsburgh have developed a digital method to transform massive amounts of gene expression data into something more image-like. Published in the Proceedings of the National Academy of Science, the scientists utilised an incredibly powerful deep learning method that has revolutionised methods such as facial recognition in recent years.

Interview with Arianne Shahvisi, Senior Lecturer in Ethics

Arianne Shahvisi is a Senior Lecturer in Ethics at the Brighton and Sussex Medical School. We managed to have a chat with Arianne ahead of her speaking at the Festival in Genomics, to get her take on the ‘coloniality’ of health and how the much-hyped advent of Whole Genome Sequencing might play a role in exasperating social injustices.

Treating Autism and Tourette’s with Ketamine: A Potential Treatment?

Researchers at Lancaster University have been the first to discover a genetic alteration that increases the risk of developing Autism Spectrum Disorder and Tourette Syndrome, as published in the journal Cerebral Cortex. Their findings suggest that ketamine, or related drugs, may be a useful treatment for both disorders.

Interview with Arianne Shahvisi, Senior Lecturer in Ethics

Arianne Shahvisi is a Senior Lecturer in Ethics at the Brighton and Sussex Medical School. We managed to have a chat with Arianne ahead of her speaking at the Festival of Genomics, to get her take on the ‘coloniality’ of health and how the much-hyped advent of Whole Genome Sequencing might play a role in exasperating social injustices.