Genetics

Cigarette Smoke Makes MRSA Superbug More Resistant to Antibiotics

Cigarette smoke has been found to make MRSA bacteria more resistant to antibiotics. The MRSA bacteria, s. aureus, can cause severe infections in humans. These are difficult to treat as MRSA is resistant to most commonly used antibiotics. MRSA poses a major problem in hospitals due to the high numbers of patients with open wounds […]

CRISPR Used to Find Genes that Protect Cells from Zika

A CRISPR technique has been used to identify genes in cells that enable them to survive infection of the Zika Virus. It is hoped that this development will lead to future treatments for Zika. Currently there is no vaccine or treatment specific to the Zika virus. If pregnant women contract the disease their unborn children […]

Chris Wigley Appointed CEO of Genomics England

Genomics England has today announced the appointment of Chris Wigley as Chief Executive Officer, with effect from 1 October. Chris joins Genomics England from QuantumBlack, a world leader in machine learning and artificial intelligence. Machine learning is critical in the analysis of the vast amounts of data involved in genomics, so Chris’ expertise in this […]

Being a Dog Lover is in Your Genes

Genetic factors contribute to how likely you are to own a dog, a new study has revealed. Evidence points to dogs being domesticated as early as 15,000 years ago. However, there is not much understanding to how this happened and if genetic factors had any influence. There is also debate if genetic influences could contribute […]

Genetic Similarities of Rare Bone Cancer Between Children and Dogs

A rare and difficult to cure bone cancer in children has been found to have significant genetic similarities with the same type of cancer in dogs. This insight could improve understanding of the disease and lead the development of more effective treatments. Osteosarcoma (OS) is a rare bone cancer in children, but relatively common in […]

Scientists Engineer Proteins into Never-Ending Patterns

Scientists have engineered proteins to form fractal geometric shapes with never-ending patterns, closely resembling those found in nature. The protein patterns could have applications in next-generation biomaterials. Fractal geometric shapes make extremely useful biomaterials as they have large surface to volume ratios, allowing rapid exchange of materials. This makes them ideal for applications both in […]

UK Government Announces Genomics Policies

As it is announced that Boris Johnson will be the next UK Prime Minister, the UK government has released their genomic policies for the 2020s. The policies aim to ‘build on [the Uk’s] position as a world leader in genomics.’ From 2023-2034 the NHS aims to analyse five million genomes and fully sequence one million […]

Drug-Resistant Malaria Spreads Across Asia

A genomics study has revealed that a strain of malaria resistant to both drugs used for treatment has spread rapidly across Asia.  Malaria causes approximately a million deaths worldwide in each year and is a serious public health issue, particularly in Asia. The widely used anti-malarial drugs dihydroartemisinin and piperaquine have been relatively effective treatments […]

New Approaches to the Old Hunt for NASH Therapies – Webinar Summary

Front Line Genomics brought together thought leaders from around the world to discuss New Approaches to the Old Hunt for NASH Therapies, available to watch on-demand. The conversation was moderated by Donna Cryer, the President and CEO of the Global Liver Institute. The panel discussed why there has been limited progress in therapies for nonalcoholic […]

Genetic Study Identifies Diabetes Gene in African Populations

The largest scale genomic study in Africa has identified a new gene that is linked to the onset of diabetes in African populations. Interestingly, the gene has not been found to be linked to diabetes in European populations.   In type 2 diabetes the body is able to produce insulin but the body’s cells do […]

False Genetic Testing Results Condemned by Doctors

The inaccuracy of a genetic test that gave false positives to patients has resulted in doctors calling for a crackdown on genetic testing. If a woman’s BCRA gene is faulty,  her risk of breast and ovarian cancer is much higher than average. People with a family history of these cancers are often tested to identify […]

Digital DNA: Hacking DNA Databases – An Interview with Peter Ney

The Digital DNA series will explore the role of large-scale genetic testing in science, industry and society. We aim to understand both the benefits and risks of this emerging technology and see what the future may hold. In the first of our Digital DNA series, we talked to Dr. Peter Ney, a researcher in the […]

Gene Editing Induces Hallucinations in Mice

Scientists have genetically engineered neurons in mice to give them hallucinations. The research could help identify why certain people experience hallucinations, associated with several mental illnesses, and inform new treatments. Two genes were inserted into the neuron cells of the mice’s visual cortex, the part of the brain that processes visual information. One coded for […]

Gender Affects Gene Expression in Mammals

Although it has been known that different genes determine different characteristics in male and females, new research suggests that differences in gene expression has a much larger impact than previously thought. Many diseases and traits show difference between the sexes. For example, autism is more common in males than females, but multiple sclerosis is more […]