Mutation ‘Hotspots’ in DNA Gives New Insights on Cancer Risks
New research from Indiana University has identified “hotspots” in DNA where the risk for genetic mutations is significantly elevated.
Genetics
How Summer and Diet Damage Your DNA, and What You Can Do
Scientists have long thought that regions of DNA called telomeres control how long you live. We are now learning that it is your diet and lifestyle that shape your telomeres, not the other way around.
Detection of GBA Missense Mutations and Other Variants Using Oxford Nanopore’s MinION’
GBA analysis is complicated by the presence of a nearby pseudogene. A new method is presented for sequencing GBA, using an amplicon including all coding regions and introns, on the MinION, enabling a fast and comprehensive assessment.
Can Scientists Leverage Mysterious Mossy Cells for Brain Disease Treatments?
A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders.
Naturally Occuring Disease in Monkeys Mimics Deadly Childhood Neurogenerative Disorder
Scientists have discovered a naturally occurring disease in monkeys that mimics a deadly childhood neurodegenerative disorder in people — a finding that holds promise for developing new gene therapies to treat Batten disease.
New Arthritis Severity Gene Found
A new gene associated with disease severity in models of rheumatoid arthritis has been identified by researchers at the Icahn School of Medicine at Mount Sinai.
Researchers Characterize ‘Mutational Burden’ Of Induced Pluripotent Stem Cells
By identifying and characterizing specific types of mutations in individual cell lines, using a combination of whole genome sequencing and multi-omic approaches, researchers hope to improve stem cells’ therapeutic uses and potential.
Scientists Link More Than 1,000 Gene Variants To Educational Attainment
Although primarily influenced by environmental and social factors, years of schooling are also influenced by genes associated with cognitive function such as memory and personality traits.
Imaging in Living Cells Reveals How ‘Junk DNA’ Switches on a Gene
New video shows how pieces of DNA once thought to be useless can act as on-off switches for genes.
Largest Genetic Database On Alzheimer’s Disease Now Re-Open For Business
The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) will begin making large-scale DNA sequence data available to investigators.
Blindness Gene Discovered
UNIGE researchers have identified the gene responsible for a recessive genetic disorder that causes degeneration of the eye and blindness.
Molecular Diagnostics Report
Read our report on all things Molecular Diagnostics, including some great contributed articles. Need to know about liquid biopsies? Want to know what the current regulatory landscape looks like? Then you’ve come to the right place.
Lawmaker’s Crack Down on the Privacy Policies of Genetic Testing Companies
US representatives are pressing genetic testing companies for details on their security systems and customer privacy policies.
The Truth About Genetic Based Dietary Plans
A comprehensive analysis of published research, suggests that there is not enough evidence to claim genetic links to dietary recommendations.
The Cause of Prostate Cancer Progression Has Likely Been Uncovered
Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism (SNP) rs11672691 influences prostate cancer aggressiveness.
