Precision medicine is showing significant signs of success across tumour types.
Scientists at Dana-Farber Cancer Institute have solved a mystery that has lingered ever since the dangers of the drug first became apparent: how did the drug produce such severe fetal harm?
New research from Indiana University has identified “hotspots” in DNA where the risk for genetic mutations is significantly elevated.
Scientists have long thought that regions of DNA called telomeres control how long you live. We are now learning that it is your diet and lifestyle that shape your telomeres, not the other way around.
GBA analysis is complicated by the presence of a nearby pseudogene. A new method is presented for sequencing GBA, using an amplicon including all coding regions and introns, on the MinION, enabling a fast and comprehensive assessment.
A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders.
Scientists have discovered a naturally occurring disease in monkeys that mimics a deadly childhood neurodegenerative disorder in people — a finding that holds promise for developing new gene therapies to treat Batten disease.
By identifying and characterizing specific types of mutations in individual cell lines, using a combination of whole genome sequencing and multi-omic approaches, researchers hope to improve stem cells’ therapeutic uses and potential.
Although primarily influenced by environmental and social factors, years of schooling are also influenced by genes associated with cognitive function such as memory and personality traits.
New video shows how pieces of DNA once thought to be useless can act as on-off switches for genes.
The National Institute on Aging Genetics of Alzheimer’s Disease Data Storage Site (NIAGADS) will begin making large-scale DNA sequence data available to investigators.