Researchers at the Key Laboratory of Synthetic Biology in Shanghai have used CRISPR to create a new species of yeast that only has a single giant chromosome.
Altering the genome, typically to better understand gene and protein function. This also paves the way for gene therapy.
To find out which DNA repair enzymes are critical to homology-directed repair after CRISPR cutting, researchers have knocked out, one at a time, more than 2,000 genes known or suspected to be involved in DNA repair, a function critical to a healthy cell.
The NIH has committed up to $45.5M to support its Somatic Cell Genome Editing programme. The money will make up a series of grants to be paid over the next four fiscal years.
Americans are more likely to anticipate negative than positive effects from widespread use of gene-editing technology.
Prenatal gene therapy has been used to prevent acute neuronopathic Gaucher’s disease, however this approach is using viruses to deliver normal copies of genes.
Scientists have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought.
The Nuffield Council on Bioethics has concluded that using gene editing tools on human embryos, sperm, or eggs for heritable gene editing could be ‘morally permissible’ in some cases.
Scientists are taking advantage of the “self-homing” abilities of cancer cells and are creating armies of cancer-killing cells using CRISPR gene-editing.
Researchers have for the first time, used gene-editing tools in adult monkeys to disable a gene throughout much of the liver.
Researchers have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model.
New research could allow us greater control over what happens to genetically modified organisms once they’re in the wild.