He Jiankui, the Chinese scientist who stunned the world by announcing the birth of two CRISPR-edited twins this week, has claimed that another woman is already pregnant with a separate CRISPR baby.
Altering the genome, typically to better understand gene and protein function. This also paves the way for gene therapy.
Twin girls in China have allegedly been born after having their embryonic genetic code modified using CRISPR. Chinese researcher He Jiankui, from the Southern University of Science and Technology, claims to have turned off a gene called CCR5 to offer total protection against HIV, as well as smallpox and cholera.
Researchers at the Chinese Academy of Sciences have used two female mice to create offspring which subsequently went on to have healthy children of their own. While similar offspring were produced from two male mice, they did not survive for longer than a few days.
For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.
Researchers at the Key Laboratory of Synthetic Biology in Shanghai have used CRISPR to create a new species of yeast that only has a single giant chromosome.
To find out which DNA repair enzymes are critical to homology-directed repair after CRISPR cutting, researchers have knocked out, one at a time, more than 2,000 genes known or suspected to be involved in DNA repair, a function critical to a healthy cell.
The NIH has committed up to $45.5M to support its Somatic Cell Genome Editing programme. The money will make up a series of grants to be paid over the next four fiscal years.
Americans are more likely to anticipate negative than positive effects from widespread use of gene-editing technology.
Prenatal gene therapy has been used to prevent acute neuronopathic Gaucher’s disease, however this approach is using viruses to deliver normal copies of genes.
Scientists have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought.
The Nuffield Council on Bioethics has concluded that using gene editing tools on human embryos, sperm, or eggs for heritable gene editing could be ‘morally permissible’ in some cases.