GWAS

Lack of Diversity Harms Schizophrenia Studies

Schizophrenia is one of the most common serious mental health conditions, with a 1% global lifetime risk. By gathering data from a non-European population, a study published in Nature Genetics has discovered that there are differences in genetic associations with schizophrenia that differ across ancestries.

How diversity in genetic research can save lives

Our guest contributor Dr Neil Lamb continues his fortnighty Shareable Science Blog. Neil is the Vice President for Educational Outreach at the HudsonAlpha Institute for Biotechnology and Shareable Science will explore how genetics is relevant to people in their everyday lives.  In many ways, genetics boils down to a study of diversity. Humans share more […]

The Genetics of Suicidal Behaviour

Suicide is UK’s leading, and silent, cause of death for young people aged 20-34 years. Rona Strawbridge, UKRI Innovation, has used the population genomic data from the UK Biobank in an effort to find the genetic association of psychological condition phenotypes such as depression.  She will be discussing her work at the upcoming Festival of Genomics. […]

ATCC Genome Portal Provides Access to Reference-quality Genomes

Manassas, VA – October 1, 2019 – ATCC launched its new ATCC Genome Portal, a publicly available database of reference-quality genome sequences matched to authenticated ATCC biological materials that will help researchers interpret and reproduce their results with confidence. The portal, which launched with an initial 250 genome sequences of widely used bacterial strains, delivers […]

Psoriasis Drugs Could be Repurposed as Osteosarcoma Treatments

Psoriasis drugs could be repurposed as osteosarcoma treatments, as both diseases respond to inhibition of the same target. Osteosarcoma is a rare and difficult to cure bone cancer in children. Survival outcomes for children are poor, even with surgery and chemotherapy, as approximately 30% of patients die within five years of a diagnosis. However, increased […]

Genetic Basis for Being Left Handed Identified

Being left-handed could be down to differences in brain architecture, a new study has shown. Only 10% of the population are left-handed, as has been the case for thousands of years, but previous studies have struggled to identify the reasons behind this. Using data from the UK Biobank, the genomes of 400,000 people, including 38,332 […]

Queering the Genome – Are We Ready?

It has been less than a week since the landmark study into the genetics of same-sex sexual behaviour first broke and sparked debate across the twitterverse. There has been much disagreement amongst the scientific and LGBTQ+ communities alike, regarding whether this research should have been conducted at all. Conversely, many have praised the study for […]

Genomics Medicine Ireland Announces Strategic Advisory Board

Genomics Medicine Ireland (GMI) has announced the establishment of a Strategic Advisory Board that will work collaboratively with GMI in shaping the company’s strategy for the application of large-scale genomics population studies on the island of Ireland, in addition to providing input and advice on the multi-disciplinary integration of genomics into the Irish healthcare system. […]

Biobank 2019 — An Interview with Professor Joshua Denny, Vanderbilt University Medical Center

The UK Biobank’s 2019 scientific conference concluded this month, showcasing fantastic speakers on topics ranging from use of the UK Biobank, to using genomics to understand individual risk. Among them was Professor Josh Denny, Vanderbilt University. FLG spoke to him about his talk on phenome-wide association studies (PheWAS): a research technique used to understand what disease associations can be made with a given gene.