An evolutionary survival mechanism that helped early humans avoid starvation could be behind the obesity epidemic in society today. Starvation puts considerable stress on cells. The body responds with a mechanism that blocks fat from burning when the body is starving, injured or cold. This enables energy to be conserved so people can survive longer, […]
Genomics will change what patients expect from their provider, as well as change how physicians treat them. Before this happens, education on both sides is needed. This month we look at some of the big talking points.
Researchers have revealed the first vaccine purely designed by artificial intelligence (AI). This has the potential to revolutionise the drug discovery process by making it quicker, cheaper and producing more effective drugs. From target discovery to market, the drug discovery process takes on average nine years and millions of dollars. The majority of this time […]
The UK Biobank’s 2019 scientific conference concluded this month, showcasing fantastic speakers on topics ranging from use of the UK Biobank, to using genomics to understand individual risk. Among them was Professor Josh Denny, Vanderbilt University. FLG spoke to him about his talk on phenome-wide association studies (PheWAS): a research technique used to understand what disease associations can be made with a given gene.
Epitranscriptomics – An Interview with Samie Jaffrey, Professor of Pharmacology, Weill Cornell Medicine
The study of epitranscriptomics has ramifications for better understanding disease symptoms and pushing forward drug treatment. But it’s also an emerging area still misunderstood by many. FLG spoke to Dr Samie Jaffrey, Professor of Pharmacology, Weill Cornell Medicine, about the field.
A new genetic study has revealed anorexia, previously thought to be solely a psychiatric disease, is influenced by metabolic factors. Anorexia is an eating disorder and a serious mental health condition. Sufferers try to keep their weight as low as possible by eating as little as possible or exercising as much as they can. Sufferers […]
Researchers have developed a new technique to pinpoint immune cells in cancer patients that are reactive against their disease. This research could lead to more targeted immune-based therapies for cancer patients. Immunotherapy is a relatively new field of cancer treatment which works by promoting the patient’s immune system to fight against the cancer. Although immune […]
A study has shown that you can reduce your risk of getting dementia by adapting a healthy lifestyle, regardless of your genetic pre-disposition. Genetic factors can increase a person’s likelihood of getting dementia, but until now it was not known if making lifestyle changes could reduce this risk. 196,383 individuals above 60 years of age […]
A new treatment for malnourished children, using food that promotes a healthy microbiome, has been found to aid recovery better than current alternatives. Malnourished children often struggle to recover and find gaining weight again extremely difficult, even with sufficient food. Scientists have long suspected this is due to the role of the gut microbiome. Gut […]
The French Healthcare Minister has announced that the government will stop the funding of homeopathic remedies by 2021. It is estimated that the policy will save €127 million ($142.30 million). Homeopathy is an alternative medicine practice based on the philosophy that ‘like cures like.’ For example, if an ill person is displaying certain symptoms then […]
From September 2019 boys in England will be offered the HPV vaccine free on the NHS to reduce the spread of HPV related cancers. England will join Scotland and Australia in making the vaccine available to both genders to extend its successful immunisation programme. Human papillomavirus (HPV) causes the majority of cervical cancers cases in […]
A variant of the common cold virus has shown promising trial results as a treatment for bladder cancer. Bladder cancer is the tenth highest incident cancer in the UK and kills approximately 5,300 people a year. Current treatments for bladder cancer mostly have high recurrence rates or dangerous side-effects. 15 non-muscle invasive bladder cancer patients […]
Patients with a certain genetic variant have been found to both be more pre-disposed to anxiety and depression and have lower susceptibility to the usual medication. Although anxiety and depression can be developed due to distressing events or stressful periods in a person’s life, there is increasing evidence that some people are more predisposed to […]
NASH is present in nine to 18 million people in America alone. Yet no single drug has yet been approved for its treatment. To discuss why therapies are proving so elusive, and where efforts will be made in the future, FLG has gathered some of the most influential names in the field to discuss the problem in our latest webinar: New Approaches to the Old Hunt for NASH Therapies, held at 4pm on 11 July 2019.
A new genetic test has been successfully trialled at a hospital in Oxford to help doctors identify patients most at risk of chemotherapy side-effects. Capecitabine and fluorouracil (5FU) are common chemotherapy drugs for cancers including breast, bowl and stomach. Both drugs act as anti-metabolites and resemble biological molecules found inside cells. When the drug molecules […]
Biobank 2019 – An Interview with Anthony Whetton, Professor of Cancer Cell Biology, University of Manchester
The UK Biobank’s 2019 scientific conference concluded this month. We talked to speaker Anthony Whetton, Professor of Cancer Cell Biology at the University of Manchester and Director of the Stoller Biomarker Discovery Centre, about large-scale multi-omic data within UK Biobank.