Healthcare

Genomics will change what patients expect from their provider, as well as change how physicians treat them. Before this happens, education on both sides is needed. This month we look at some of the big talking points.

Changes in Gut Microbiota Implicated in Colorectal Cancer

Gut microbiota has wide reaching effects on health and disease. A study published in Proceedings of the National Academy of Sciences, PNAS, has demonstrated that gut imbalance promotes the onset of colorectal cancer, going on to invent a blood test to identify the epigenetic signatures.

Lack of Diversity Harms Schizophrenia Studies

Schizophrenia is one of the most common serious mental health conditions, with a 1% global lifetime risk. By gathering data from a non-European population, a study published in Nature Genetics has discovered that there are differences in genetic associations with schizophrenia that differ across ancestries.

Research Suggests New Approach to Combat Antimicrobial Resistant Malaria

The rise of antimicrobial resistant malaria, especially across Asia, has caused great concern and a hunt for new drugs and treatment. A collaborative group across Europe have systematically deleted genes from Plasmodium berghei and uncovered 7 metabolic pathways crucial for the life cycle of the parasite.

Measles Can Wipe Immune System Memory

New research has shown that measles infection can cause part of the immune system memory to be deleted, taking away the body’s previously acquired immunity to other infections. It is known that measles damages the immune system, as children infected with measles are more prone to other infections once they recover. Children can show immune […]

Health Education England Present New Competency Framework for Genomic Testing

New competency framework for genomic testing The Genomics Education Programme (GEP) has developed a cross-professional framework to support clinicians facilitating genomic testing With the roll-out of the NHS Genomic Medicine Service, patients across England gain equity of access to genomic testing for the first time, including whole genome sequencing for certain rare diseases and cancers. […]

Alcohol Abuse Leaves Epigenetic Marks in Brain

Alcohol has been found to directly contribute to epigenetic markers in areas of the brain involved in learning and memory. It is therefore possible that stopping epigenetic marker deposition could be a promising therapy to treat alcohol addiction. Epigenetic markers are chemical modifications on DNA bases that alter the expression of genes without editing the […]

NIH, Gates Foundation Commit $200M to Gene-Based Cures for Sickle Cell and HIV

  Press Release from National Institute of Health  The National Institutes of Health plans to invest at least $100 million over the next four years toward an audacious goal: develop affordable, gene-based cures for sickle cell disease (SCD) and HIV. The Bill & Melinda Gates Foundation will also invest $100 million toward this goal. The […]

Registration for the Festival of Genomics 2020 Now Open

Returning for its 5th consecutive year, the 2020 Festival promises to be a unique experience, a crossroads for the entire genomics ecosystem to discover, meet, learn, have fun and celebrate. It is the largest genomics event in the UK and the fastest growing genomics event in the world. The Festival delivers incredible talks, speakers, cutting-edge content, inspirational topics, […]

Ancestry DNA Begins Genetic Health Testing

The consumer genetic testing platform AncestryDNA will now offer customers genetic testing to understand their risks for a number of health conditions. From Family History to Healthcare Previously, Ancestry has exclusively focused on helping people trace their family history and understand inheritable traits. However, possibly in a bid to keep up with many of their […]

Viagra Could Transform Bone Marrow Transplants

A combination of Viagra and Plerixafor, both clinically approved drugs, could improve the efficacy of bone marrow stem cell transplants. Haemopoietic Stem cell transplants are life-saving treatments for a range of blood cancers, including lymphoma and leukaemia. The cells can differentiate into all types of blood cells to replace the abnormal cancer cells and restore […]

A Genetic Cause for SIDS is Identified

A genetic cause has been found for Sudden Infant Death Syndrome (SIDS) SIDS causes 3,000 deaths a year, due to a number of causes, some environmental and some genetic. However, this is the first time a specific genetic variant has been linked to the onset of SIDS. Newborns with the genetic variant have a defect […]

Cell Death Blocker Could Aid Regenerative Medicine

A new drug molecule that can block cell death could hold the potential for a range of regenerative treatments. Apoptosis is a form of controlled cell death that is essential for normal development and body function. The BLC-2 family of proteins control the process, with some protein molecules promoting cell survival and others promoting cell […]

Translating Metastasis Research into New Models and Therapies

Understanding and tackling metastatic cancer is the single biggest opportunity to improve outcomes for the most cancer patients. But it also represents a huge opportunity to (1) improve the development of existing cancer drugs, (2) reverse declining clinical success rates in oncology, (3) drive the development of new therapies, (4) treat more aggressive cancers and […]

Psoriasis Drugs Could be Repurposed as Osteosarcoma Treatments

Psoriasis drugs could be repurposed as osteosarcoma treatments, as both diseases respond to inhibition of the same target. Osteosarcoma is a rare and difficult to cure bone cancer in children. Survival outcomes for children are poor, even with surgery and chemotherapy, as approximately 30% of patients die within five years of a diagnosis. However, increased […]