Healthcare

Genomics will change what patients expect from their provider, as well as change how physicians treat them. Before this happens, education on both sides is needed. This month we look at some of the big talking points.

New Technique to Select Offspring Gender

A reversible chemical technique can separate sperm carrying X chromosomes from sperm carrying Y chromosomes to select the offspring sex of mice. Cells from male mammals contain both an X and Y chromosome. However, sperm cells contain either an X or Y chromosome. As the female egg cell always contains an X chromosome, sperm that […]

New Drug Could Speed up Blood Cell Recovery after Chemotherapy

A drug that speeds up the regeneration of both mouse and human blood stem cells after radiation exposure could be used to successfully mitigate the side-effects of chemotherapy. Although radiation chemotherapy can be an effective cancer treatment, as it preferentially targets cancer cells over normal body cells, it can cause long lasting side-effects in patients. […]

Keto Diet Supresses Cancer Growth in Mice

Mice fed on a keto diet alongside an anti-diabetic drug were found to have slower progression rates of squamous cell carcinoma (SCC) lung tumours. The keto diet, currently widely popular, minimises sugar and carbohydrate intake. SCC is a type of cancer formed by the squamous cells that make up the epithelial layer of organs, including […]

Cyber Organoids Let Scientists Observe Cell Development

Scientists have successfully grown a ‘cyber organoid,’ a simplified organ formed from stem cells with integrated electrochemical sensors to observe its development. Organs are formed by the self-assembly of stem cells into complex 3D structures. However, due to the difficulty of monitoring this process there are still significant gaps in scientists’ understanding. Electrochemical sensors have […]

World Metastasis Summit 2019 Launch

When cancer cells break off from their initial tumour they can spread throughout the body and invade other organs to form new tumours, in a process known as metastasis. Metastatic tumours cause patients to develop stage IV or advanced cancer and are responsible for over 90% of deaths in cancer patients. In the past, cancer […]

Interview – Cath Stanley, CEO of the Huntington’s Disease Association

We talked to Cath Stanley, the CEO of the Huntington’s Disease Association. The charity offers support to those affected by Huntington’s, as well as carers and healthcare professionals, to ensure patients get the best care available. FLG: What is Huntington’s disease and What Are the Symptoms? CS: Huntington’s disease is a rare genetic disorder. It […]

First Artificial Human Liver Created

Researchers have created the first artificial human liver model from genetically engineered human liver cells. It is hoped that the artificial liver will be an effective model to study fatty liver diseases. Non-alcoholic fatty liver disease (NAFLD) is a condition where fat builds up in the liver, eventually leading to liver failure. There is currently […]

Multi-Drug Resistant Bacteria Found Throughout London

Bacteria resistant to multiple antibiotic drugs have been found throughout London, including on the underground and in hospitals, new research shows. Antibiotic resistant bacteria are a serious public health issue, which make the treatment of many infections difficult. Bacteria can acquire resistance either through the selection pressure of antibiotics, or from genetic transfer between cells. […]

CRISPR Activation Technique Improves Muscular Dystrophy Symptoms in Mice

A CRISPR activation technique has been shown to improve the symptoms of muscular dystrophy disease in mice. Muscular dystrophy is a hereditary condition characterised by progressive weakening and wasting of the muscles. A specific type of muscular dystrophy is caused by mutations in the gene Lama2, which codes for the protein laminin. Mutations in the […]

WHO Releases Statement Condemning Further Germline Genome Editing

The World Health Organisation (WHO) has released a statement calling for a stop to germline editing in humans. This is in light of recent controversial experiments in the field which emphasized patient safety concerns. Germline editing refers to the genome editing of reproductive cells. These changes are inheritable, and the technology has the potential to […]

Cigarette Smoke Makes MRSA Superbug More Resistant to Antibiotics

Cigarette smoke has been found to make MRSA bacteria more resistant to antibiotics. The MRSA bacteria, s. aureus, can cause severe infections in humans. These are difficult to treat as MRSA is resistant to most commonly used antibiotics. MRSA poses a major problem in hospitals due to the high numbers of patients with open wounds […]

Chris Wigley Appointed CEO of Genomics England

Genomics England has today announced the appointment of Chris Wigley as Chief Executive Officer, with effect from 1 October. Chris joins Genomics England from QuantumBlack, a world leader in machine learning and artificial intelligence. Machine learning is critical in the analysis of the vast amounts of data involved in genomics, so Chris’ expertise in this […]

Gene Discovery Explains Failure of Alzheimer’s Drugs

A gene discovery has explained why current Alzheimer’s drugs don’t work for lots of patients, and why so many new drugs fail in clinical trials. The acetylcholine receptor α7nAChR has long been a target of interest for Alzheimer’s drugs. The neurotransmitter acetylcholine is involved in memory and learning processes. Despite acetylcholine being linked to the […]