Microbes are well known to form entire communities in our guts – or microbiomes, but less is known about the communities we have in our lungs. Researchers from Washington University School of Medicine in St. Louis investigated the correlation between microbial colonisation in the upper airway and the severity of asthma symptoms
Genomics will change what patients expect from their provider, as well as change how physicians treat them. Before this happens, education on both sides is needed. This month we look at some of the big talking points.
We met with Chris Wigley, CEO and Sir Mark Caulfield, Chief Scientist at Genomics England, at the first Genomics England Research conference taking place in November 2019 in London. We started by asking them how Genomics England is getting on with their objectives.
A study published in Scientific Reports examined nearly 1,400 mother-child pairs from a multi-centre European birth cohort and found that childhood obesity was associated with shorter telomeres. Telomere length is a useful biomarker of biological ageing, as shorter telomeres are associated with a wide range of diseases. These encompass cancer, premature ageing, and obesity.
The immunotherapy drug Blinatumomab has shown to be an effective treatment for children and young adults with relapsed B-cell acute lymphoblastic leukaemia in a clinical trial led by the Children’s Oncology Group, part of the National Cancer Institute USA, and presented at the annual meeting at the American Society of Haematology.
Researchers at Lancaster University have been the first to discover a genetic alteration that increases the risk of developing Autism Spectrum Disorder and Tourette Syndrome, as published in the journal Cerebral Cortex. Their findings suggest that ketamine, or related drugs, may be a useful treatment for both disorders.
The Environmental Determinants of Diabetes in the Young or TEDDY is the largest study of its kind measuring new-borns with an increased risk of Type 1 Diabetes (T1D). The study published in Nature Medicine has uncovered an association between a genetic variant of a pancreatic cell surface-receptor and long-term viral infections.
Brain networks associated with suicide have been identified by examining brain images from the past two decades. The study published in Molecular Psychiatry found changes in the prefrontal cortex were important risk factors in suicidal thoughts and behaviours. 800,000 people die globally by suicide every year – one every 40 seconds. It is the second […]
A study from the Salk Institute and Massachusetts Institute of Technology has identified a new brain circuit implicated in compulsive drinking in mice and how to modify it to discourage binge drinking.
Gut microbiota has wide reaching effects on health and disease. A study published in Proceedings of the National Academy of Sciences, PNAS, has demonstrated that gut imbalance promotes the onset of colorectal cancer, going on to invent a blood test to identify the epigenetic signatures.
Schizophrenia is one of the most common serious mental health conditions, with a 1% global lifetime risk. By gathering data from a non-European population, a study published in Nature Genetics has discovered that there are differences in genetic associations with schizophrenia that differ across ancestries.