A rare and difficult to cure bone cancer in children has been found to have significant genetic similarities with the same type of cancer in dogs. This insight could improve understanding of the disease and lead the development of more effective treatments. Osteosarcoma (OS) is a rare bone cancer in children, but relatively common in […]
Genomics will change what patients expect from their provider, as well as change how physicians treat them. Before this happens, education on both sides is needed. This month we look at some of the big talking points.
As it is announced that Boris Johnson will be the next UK Prime Minister, the UK government has released their genomic policies for the 2020s. The policies aim to ‘build on [the Uk’s] position as a world leader in genomics.’ From 2023-2034 the NHS aims to analyse five million genomes and fully sequence one million […]
A genomics study has revealed that a strain of malaria resistant to both drugs used for treatment has spread rapidly across Asia. Malaria causes approximately a million deaths worldwide in each year and is a serious public health issue, particularly in Asia. The widely used anti-malarial drugs dihydroartemisinin and piperaquine have been relatively effective treatments […]
Front Line Genomics brought together thought leaders from around the world to discuss New Approaches to the Old Hunt for NASH Therapies, available to watch on-demand. The conversation was moderated by Donna Cryer, the President and CEO of the Global Liver Institute. The panel discussed why there has been limited progress in therapies for nonalcoholic […]
The largest scale genomic study in Africa has identified a new gene that is linked to the onset of diabetes in African populations. Interestingly, the gene has not been found to be linked to diabetes in European populations. In type 2 diabetes the body is able to produce insulin but the body’s cells do […]
The inaccuracy of a genetic test that gave false positives to patients has resulted in doctors calling for a crackdown on genetic testing. If a woman’s BCRA gene is faulty, her risk of breast and ovarian cancer is much higher than average. People with a family history of these cancers are often tested to identify […]
The Digital DNA series will explore the role of large-scale genetic testing in science, industry and society. We aim to understand both the benefits and risks of this emerging technology and see what the future may hold. In the first of our Digital DNA series, we talked to Dr. Peter Ney, a researcher in the […]
An evolutionary survival mechanism that helped early humans avoid starvation could be behind the obesity epidemic in society today. Starvation puts considerable stress on cells. The body responds with a mechanism that blocks fat from burning when the body is starving, injured or cold. This enables energy to be conserved so people can survive longer, […]
Researchers have revealed the first vaccine purely designed by artificial intelligence (AI). This has the potential to revolutionise the drug discovery process by making it quicker, cheaper and producing more effective drugs. From target discovery to market, the drug discovery process takes on average nine years and millions of dollars. The majority of this time […]
The UK Biobank’s 2019 scientific conference concluded this month, showcasing fantastic speakers on topics ranging from use of the UK Biobank, to using genomics to understand individual risk. Among them was Professor Josh Denny, Vanderbilt University. FLG spoke to him about his talk on phenome-wide association studies (PheWAS): a research technique used to understand what disease associations can be made with a given gene.
Epitranscriptomics – An Interview with Samie Jaffrey, Professor of Pharmacology, Weill Cornell Medicine
The study of epitranscriptomics has ramifications for better understanding disease symptoms and pushing forward drug treatment. But it’s also an emerging area still misunderstood by many. FLG spoke to Dr Samie Jaffrey, Professor of Pharmacology, Weill Cornell Medicine, about the field.
A new genetic study has revealed anorexia, previously thought to be solely a psychiatric disease, is influenced by metabolic factors. Anorexia is an eating disorder and a serious mental health condition. Sufferers try to keep their weight as low as possible by eating as little as possible or exercising as much as they can. Sufferers […]
Researchers have developed a new technique to pinpoint immune cells in cancer patients that are reactive against their disease. This research could lead to more targeted immune-based therapies for cancer patients. Immunotherapy is a relatively new field of cancer treatment which works by promoting the patient’s immune system to fight against the cancer. Although immune […]
A study has shown that you can reduce your risk of getting dementia by adapting a healthy lifestyle, regardless of your genetic pre-disposition. Genetic factors can increase a person’s likelihood of getting dementia, but until now it was not known if making lifestyle changes could reduce this risk. 196,383 individuals above 60 years of age […]
A new treatment for malnourished children, using food that promotes a healthy microbiome, has been found to aid recovery better than current alternatives. Malnourished children often struggle to recover and find gaining weight again extremely difficult, even with sufficient food. Scientists have long suspected this is due to the role of the gut microbiome. Gut […]