Immunotherapy

Blinatumomab – Improving Outcomes for Children with Relapsed Leukaemia

The immunotherapy drug Blinatumomab has shown to be an effective treatment for children and young adults with relapsed B-cell acute lymphoblastic leukaemia in a clinical trial led by the Children’s Oncology Group, part of the National Cancer Institute USA, and presented at the annual meeting at the American Society of Haematology.

Artificial Enzymes Improve Immunotherapy Treatments

Artificial nanoenzymes have shown promise in improving both the selectivity and efficacy of immunotherapy treatment. Only a small proportion of patients see the benefits of immunotherapy as tumour cells can employ a multitude of disguises to avoid detection by the immune system. Too ensure more patients can experience the benefits of immunotherapy, new technologies are […]

Oxygen Starved Cancer Cells Recruit Immune Cells to Survive

  Pancreatic cancer cells can recruit immune cells to restore their oxygen supply in response to anti-angiogenesis therapies. To maintain their nutrient and oxygen supplies tumour cells initiate the formation of new blood vessels, in a process known as angiogenesis. Many cancer therapies work by blocking angiogenesis, as the process does not usually occur in […]

New Technique to Help Immune System Find Hidden Cancer Cells

Cancer cells are prone to disguising themselves from the immune system to avoid detection. However, a new system can pinpoint cancer cells to allow the immune system to eliminate the tumour. Immunotherapy is a cancer treatment that harnesses the body’s immune system to fight cancer cells. Although immunotherapies have completely transformed the cancer treatment landscape, […]

Targeting Immune Cells Could Offer Potential Alzheimer’s Therapy

Targeting the immune cells in the brain could slow down the onset of Altzheimer’s, a new study has shown. The build-up of tau protein in the brain can be indicative many neurodegenerative disorders, including Alzheimer’s. Once the tau starts to clump together, tissue damage begins to become visible. However, until recently the link between protein […]

Breathalyser Test Can Predict Which Patients Will Respond to Lung Cancer Immunotherapy

A newly developed ‘electronic nose’ can measure chemicals in the breath of small cancer lung patients to determine if they will respond to immunotherapy treatment. Immunotherapy is Changing Cancer Care Immunotherapy treatments harness the body’s immune system to fight the cancer cells, which is transforming the treatment of advanced stage cancers. However, only a small […]

Genomic Barcode Identifies Immune Cells that Can Tackle Cancer

Researchers have developed a new technique to pinpoint immune cells in cancer patients that are reactive against their disease. This research could lead to more targeted immune-based therapies for cancer patients. Immunotherapy is a relatively new field of cancer treatment which works by promoting the patient’s immune system to fight against the cancer. Although immune […]

Two Studies Find Reasons for IO Drug Resistance

Two separate studies have uncovered insights into why checkpoint-inhibiting immune-oncology (IO) drugs only work for a minority of patients, even when combined with other treatments. The first study uncovered a resistance mechanism within the gut microbiome, while the other relates to cancer cell-produced vesicles.

CAR-T Therapy Destroys Lupus in Mice

A number of mice have been cured entirely of lupus by a CAR-T treatment which wipes out the immune system’s B cells by spotting the CD19 protein marker which nearly all B cells carry.

Blocking MDSC immune cells shown to slow TNBC metastasis

A new report from the University of Pennsylvania School of Veterinary Medicine has expanded what we know about the connection between myeloid-derived immunosuppressor cells (MDSCs) and aggressive disease. Their research has found that blocking the deltaNp63 protein on tumour cells which directs MDSCs to tumour and metastatic sites, or blocking the MDSCs themselves, reduces tumour growth and metastasis in a mouse model of triple-negative breast cancer (TNBC).

What Could You Do With 10,000 Immunomes?

A database of normal human immunity has been created by scientists at UC San Francisco, creating an instant comparison group to let researchers use in studies of the immune system and immune dysfunction.

  • Page 1 of 2
  • 1
  • 2
  • >