Infectious Disease

Multi-Drug Resistant Bacteria Found Throughout London

Bacteria resistant to multiple antibiotic drugs have been found throughout London, including on the underground and in hospitals, new research shows. Antibiotic resistant bacteria are a serious public health issue, which make the treatment of many infections difficult. Bacteria can acquire resistance either through the selection pressure of antibiotics, or from genetic transfer between cells. […]

Cigarette Smoke Makes MRSA Superbug More Resistant to Antibiotics

Cigarette smoke has been found to make MRSA bacteria more resistant to antibiotics. The MRSA bacteria, s. aureus, can cause severe infections in humans. These are difficult to treat as MRSA is resistant to most commonly used antibiotics. MRSA poses a major problem in hospitals due to the high numbers of patients with open wounds […]

CRISPR Used to Find Genes that Protect Cells from Zika

A CRISPR technique has been used to identify genes in cells that enable them to survive infection of the Zika Virus. It is hoped that this development will lead to future treatments for Zika. Currently there is no vaccine or treatment specific to the Zika virus. If pregnant women contract the disease their unborn children […]

Drug-Resistant Malaria Spreads Across Asia

A genomics study has revealed that a strain of malaria resistant to both drugs used for treatment has spread rapidly across Asia.  Malaria causes approximately a million deaths worldwide in each year and is a serious public health issue, particularly in Asia. The widely used anti-malarial drugs dihydroartemisinin and piperaquine have been relatively effective treatments […]

First AI-Designed Vaccine Created

Researchers have revealed the first vaccine purely designed by artificial intelligence (AI). This has the potential to revolutionise the drug discovery process by making it quicker, cheaper and producing more effective drugs. From target discovery to market, the drug discovery process takes on average nine years and millions of dollars. The majority of this time […]

HIV Virus Eliminated from Infected Mice Cells

A new CRISPR-based method has managed to eliminate HIV in mice, for the first time potentially curing the lifelong illness of HIV/AIDs. Clinical trials will start next year to identify if the same method could be used to cure humans.   HIV is a virus which attacks the immune cells in the body, leaving it […]

CRISPR Repairs DNA Even Without Donor Template

CRISPR-Cas9 can carry out precise genome editing even without the assistance of donor DNA templates, a team of scientists from Brigham and Women’s Hospital and the Broad Institute of MIT and Harvard have found.

Human genome sequencing on PromethION: characterization of structural variants and repetitive regions

  At the VIB-UAntwerp Center for Molecular Neurology, we apply sequencing technologies to elucidate the genetic etiology of neurodegenerative brain diseases such as Alzheimer Disease and Frontotemporal Dementia. Structural variation and repetitive regions are insufficiently characterized using currently dominant short-read sequencing technologies. Long-read sequencing on the Oxford Nanopore PromethION has the potential for a comprehensive […]

Antibiotic Resistance is in the Air

An international study has found that the air in 19 cities across 13 counties contained genetic material that is known to confer antibiotic resistance in bacteria.