CRISPR-Cas9 can carry out precise genome editing even without the assistance of donor DNA templates, a team of scientists from Brigham and Women’s Hospital and the Broad Institute of MIT and Harvard have found.
We spoke to Dr. David R. Hillyard MD, Chair and Medical Director of Molecular Infectious Diseases at ARUP Laboratories, about his work within the realm of infectious diseases and the increasing role of molecular diagnostics in combating pathogens.
Human genome sequencing on PromethION: characterization of structural variants and repetitive regions
At the VIB-UAntwerp Center for Molecular Neurology, we apply sequencing technologies to elucidate the genetic etiology of neurodegenerative brain diseases such as Alzheimer Disease and Frontotemporal Dementia. Structural variation and repetitive regions are insufficiently characterized using currently dominant short-read sequencing technologies. Long-read sequencing on the Oxford Nanopore PromethION has the potential for a comprehensive […]
Scientists have discovered a naturally occurring disease in monkeys that mimics a deadly childhood neurodegenerative disorder in people — a finding that holds promise for developing new gene therapies to treat Batten disease.
Zika virus may be sexually transmissible for a shorter period than previously estimated, according to a new systematic review.
Researchers have found a genetic material related to the Ebola Virus in mouse-eared bats thats remained largely unchanged for over 18 million years. The study sheds light on the gene’s possible function in bats, suggesting that it may play a role in regulating the immune system’s response to threats.
Elementary cytoskeleton protein is different in parasites and represents a starting point for a possible new therapy against malaria infections.
Researchers at Harvard Medical School have found further evidence that supports the notion that viruses could help cause the onset of Alzheimer’s disease; an idea that was once ridiculed by other sceptics and researchers.
Even in light of the rising fears of “superbugs” in the world of big pharma, the marginal profits made through the development of antibiotics isn’t enough to justify the research.
A new analysis shows that the US health care system will save money in the long run by screening people born in Asia and Africa for the hepatitis B virus, which causes liver cancer and cirrhosis.