Mouse Artificial ‘Embryo’ Created From Stem Cells
For the first time, an artificial mouse embryo has successfully passed a critical developmental milestone in the lab.
Molecular Biology
DNA Repair After CRISPR Cutting: Not At All What People Thought
To find out which DNA repair enzymes are critical to homology-directed repair after CRISPR cutting, researchers have knocked out, one at a time, more than 2,000 genes known or suspected to be involved in DNA repair, a function critical to a healthy cell.
Molecular Diagnostics Report
Read our report on all things Molecular Diagnostics, including some great contributed articles. Need to know about liquid biopsies? Want to know what the current regulatory landscape looks like? Then you’ve come to the right place.
Drugs Could Destroy Super-Strong Bacterial Armour
Scientists have previously overlooked the astonishing physical strength of the thin outer membrane that clings to E. coli‘s stout cell wall, according to a new study.
Biological Fax Machine Delivering DNA On-Demand
Synthetic Genomics believe its ‘biological teleportation’ — a process in which DNA is digitally transmitted and printed out as synthetic sequences — will soon be mainstream.
Personalised Alzheimer’s Treatment Through Fingerprints
Personalised medicine has been a goal of researchers and doctors for a long time. Now, researchers have developed what they call a personalised Therapeutic Intervention Fingerprint (pTIF), for patients with neurological disease.
Scientists Use CRISPR to Build Cancer-Fighting Army from Its Own Tumour Cells
Scientists are taking advantage of the “self-homing” abilities of cancer cells and are creating armies of cancer-killing cells using CRISPR gene-editing.
CRISPR-Cas9 Delivered Directly to Human Sperm
The CRISPR genome editing method has been delivered directly in human sperm cells giving hope that correcting mutations in human sperm cells is possible and may lead to the prevention of disease being passed on by fathers.
Cold Temps Lead to Offspring With More ‘Good Fat’, Say Researchers
Males who spend time in low temperatures prior to mating will produce offspring with more active brown adipose tissue, according to new research in mice.
Scientists Discover the ‘Big Bang’ of Alzheimer’s Disease
Scientists have discovered a “big bang” of Alzheimer’s disease — the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.
CRISPR Approach Converts Skin Cells into Pluripotent Stem Cells
Researchers have for the first time succeeded in converting human skin cells into pluripotent stem cells by activating the cell’s own genes, using gene editing technology CRISPRa.
Technique Paves Way for Creating Medicines Without Side Effects
A new technique for precisely targeting molecules within cells is paving the way for safer medicines that are free of side effects.
Would Dialling Down This Enzyme Treat Breast Cancer?
The enzyme TLK2 displays lower levels of activity in intellectual disability, and overactivity in cases of breast cancer, say researchers.
Tagging Method Gives New View of Proteins Inside Our Cells
Scientists have created a new way to view proteins inside human cells. The method allows an electron microscope to view proteins precisely, unlike current methods.
Artificial Network Made Of DNA Identifies ‘Molecular Handwriting’
Researchers at Caltech have developed an artificial neural network made out of DNA that can solve a classic machine learning problem: Correctly identifying handwritten numbers.
