Maize is one of the most economically important crops globally and much effort has been spent generating the high quality B73 reference genome. However, the 10 chromosome, 2.3 gigabase (Gb) B73 reference genome was a substantial challenge due to the fact it is comprised of 85% transposable elements, 75% of which are long terminal […]
The development of the first automated DNA sequencers completely revolutionized the field of DNA sequencing and, eventually, made it possible to publish the first draft sequences of the human genome. Since then, a whole host of companies have developed their own approaches to DNA sequencing, resulting in a market that is filled with different possibilities […]
Researchers at the Key Laboratory of Synthetic Biology in Shanghai have used CRISPR to create a new species of yeast that only has a single giant chromosome.
To find out which DNA repair enzymes are critical to homology-directed repair after CRISPR cutting, researchers have knocked out, one at a time, more than 2,000 genes known or suspected to be involved in DNA repair, a function critical to a healthy cell.
Personalised medicine has been a goal of researchers and doctors for a long time. Now, researchers have developed what they call a personalised Therapeutic Intervention Fingerprint (pTIF), for patients with neurological disease.
Scientists are taking advantage of the “self-homing” abilities of cancer cells and are creating armies of cancer-killing cells using CRISPR gene-editing.
Males who spend time in low temperatures prior to mating will produce offspring with more active brown adipose tissue, according to new research in mice.
Scientists have discovered a “big bang” of Alzheimer’s disease — the precise point at which a healthy protein becomes toxic but has not yet formed deadly tangles in the brain.
Researchers have for the first time succeeded in converting human skin cells into pluripotent stem cells by activating the cell’s own genes, using gene editing technology CRISPRa.
A new technique for precisely targeting molecules within cells is paving the way for safer medicines that are free of side effects.