New research published in the British Journal of Cancer has identified a link between the so-called “junk DNA” and the risk of developing cancer. Junk DNA refers to regions of DNA that don’t code for proteins but are thought to play in a role in gene expression regulation
Researchers at the Wellcome Sanger Institute uncovered a possible pre-cancerous signature for Wilms’ tumour, a form of kidney cancer mainly affecting children under five years old. Published in Science, the research was the first to compare Wilms’ tumour tissue and healthy kidney tissue to identify any genetic changes that could possibly be predictive of disease progression.
A new research paper has investigated the link between the BAZ1B gene and self-domestication of humans. The same gene has been found to control much of human facial development and be involved in the domestication of dogs and cats, possibly suggesting that humans are self-domesticated.
The analysis of rare genomic copy number variants (CNVs) in siblings of a proband with autism spectrum disorder (ASD) could be used to predict the likelihood of developing ASD themselves, according to an article published today in Nature.
In late 2018, the world was shocked by the news of the birth of the first CRISPR gene edited twin babies. Chinese biophysicist He Jiankui carried out an experiment to create babies with a natural resistance to HIV by editing the CCR5 gene, known to play a role in the immune response.
A new study by Northwestern Medicine has become the first to compare gene expression levels in African American populations by studying the levels of mRNA expressed in the liver. Previous studies have compared only African and European individuals separately and this study aimed to address the “grey” area of mixed ethnicities.
Brain networks associated with suicide have been identified by examining brain images from the past two decades. The study published in Molecular Psychiatry found changes in the prefrontal cortex were important risk factors in suicidal thoughts and behaviours. 800,000 people die globally by suicide every year – one every 40 seconds. It is the second […]
An exploratory project to find fossil microbes on the Red Planet has been proposed between NASA and the European Space Agency (ESA). The possibility of finding alien life has long been an alluring concept for many and this new scheme intends to bring Martian soil to Earth for intensive study.
Self-destructing mitochondria could be the initiation step for a range of neurogenerative diseases, new research shows. Mitochondrial dysfunction has been observed in the early stages of ALS, a neurogenerative disease that affects voluntary muscle movement. The symptoms of ALS are caused by the disintegration of the upper motor neurons of the brain, which is often […]
We earlier highlighted the most important takeaways from the Genomics England Research Conference, including how the UK will work to build on its status as a world leader in genomics. We also wanted to put a spotlight on the exciting research that is using the data from the 100,000 Genomes Project. Here are Front Line […]
Returning for its 5th consecutive year, the 2020 Festival promises to be a unique experience, a crossroads for the entire genomics ecosystem to discover, meet, learn, have fun and celebrate. It is the largest genomics event in the UK and the fastest growing genomics event in the world. The Festival delivers incredible talks, speakers, cutting-edge content, inspirational topics, […]
Our guest contributor Dr Neil Lamb continues his fortnighty Shareable Science Blog. Neil is the Vice President for Educational Outreach at the HudsonAlpha Institute for Biotechnology and Shareable Science will explore how genetics is relevant to people in their everyday lives. In many ways, genetics boils down to a study of diversity. Humans share more […]