Research

New Tech Predicts Biosequence Binding in Seconds

A new technology known as “Pattern to Knowledge” (P2K) has been created by researchers at the University of Waterloo to predict the binding of biosequences in only seconds. The new development could radically speed up discovery of new drugs and reduce the need for expensive laboratory tests.

Mutations in “Guardian of the Genome” Assist Cancer in Spreading

Tumours are helped in their development by mutating the most important cancer-prevention gene, p53, scientists from Melbourne have found. The study, published in Genes and Development, found that mutant p53 prevents the regular p53 protein from activating its natural defences, increasing the risk of the cancer spreading.

Tiny Bio-Scaffold Could Perfect Stem Cell Transportation

A minuscule, biodegradable scaffold has been created to transplant stem cells and deliver drugs within the body, the Nature Communications journal has reported, which could help with treatments for Alzheimer’s and Parkinson’s diseases, as well as aging brain degeneration and spinal cord injuries.

New Drug Combination Could Halt Fibrosis

A combination of drugs has potentially been uncovered that could halt the progression of fibrosis, a disease thought to be responsible for almost half of all deaths, according to a new study.

AMP 2018: An Interview with Dr. Jonathan Rothberg

Dr. Jonathan Rothberg is a man who needs little introduction, and is now receiving the Association of Molecular Pathology’s (AMP) Award for Excellence in Molecular Diagnostics Services. We spoke to him about his many achievements, his proudest moments, and the future of his fascinating field.

AMP 2018: Supporting Cancer Sufferers With the Mesothelioma Cancer Alliance

Given that Front Line Genomics was started after its founder’s father was diagnosed with Mesothelioma, it’s naturally a cause that we care passionately about. To that end we sat down with the Mesothelioma Cancer Alliance (MCA), an organisation dedicated to providing resources, information, and support to individuals suffering from mesothelioma and other asbestos-related diseases and their families, to find out more about the great work they do and the challenges they face every day. 

Cancer “Kill Code” Could be Naturally Embedded in Every Cell

Every single cell in the human body could contain a cancer “kill code” set to destroy cells which become cancerous, a new study reported in Nature Communications. The study, conducted by Northwestern University in the US, found that cancer cannot become resistant to this code, making it a potentially incredibly effective treatment.

Maize genome complexity traversed with Oxford Nanopore technology

  Maize is one of the most economically important crops globally and much effort has been spent generating the high quality B73 reference genome. However, the 10 chromosome, 2.3 gigabase (Gb) B73 reference genome was a substantial challenge due to the fact it is comprised of 85% transposable elements, 75% of which are long terminal […]

Scientists Uncover Why Some Cancers Affect Only Young Women

Cells settling in an organ other than the correct one during embryogenesis are often the cause of rare ovarian and pancreatic cancers which affect only young women, researchers at the University of Geneva (UNIGE) and the University Hospitals of Geneva (HUG) have found.

102 Genes Linked to Autism Spectrum Disorder

Researchers undertaking the largest genetic sequencing study of autism spectrum disorder (ASD) ever have identified 102 genes associated with the disorder, as opposed to the previous 65 in 2015, a move which they say will help greatly in differentiating ASD-related genes from those associated with intellectual disability and development delay.

Immature human eggs created from blood cells

Japanese scientists have created an immature human egg using stem cells created from blood cells, as reported in the Science journal. Although such eggs have been created in a lab before, this is the first time human blood has been used to do it.