Oxford Nanopore has launched its two new “109” cDNA kits, which provide high throughput while generating complete sequences of full-length cDNA strands with a low input option of just 1ng PolyA+ RNA.
The transcriptome gives a fuller picture of how genes are expressed. RNA sequencing allows for more detailed information on cellular pathways and expression levels in cancer studies.
Laurent Neau, Lead Technician at the Philip Morris International Tissue Research Laboratory, talks about RNAscope®, a novel and increasingly popular technology developed by Advanced Cell Diagnostics, Inc. for the in situ analysis of RNA within fixed tissues, now optimised for use on 3D, organotypic cell cultures. Doing this has the potential to provide a window into gene expression as it occurs in the human body.
Single nucleotide variations could be the key to better identification of tumour subpopulations
Neural networks and supervised machine learning (ML) techniques can characterise cells studied using single cell RNA-sequencing (scRNA-seq), scientists from Carnegie Mellon University (CMU) have learnt. This could aid others in identifying new cell subtypes and in discerning diseased cells.
Every single cell in the human body could contain a cancer “kill code” set to destroy cells which become cancerous, a new study reported in Nature Communications. The study, conducted by Northwestern University in the US, found that cancer cannot become resistant to this code, making it a potentially incredibly effective treatment.
The development of the first automated DNA sequencers completely revolutionized the field of DNA sequencing and, eventually, made it possible to publish the first draft sequences of the human genome. Since then, a whole host of companies have developed their own approaches to DNA sequencing, resulting in a market that is filled with different possibilities […]
Scientists have long thought that regions of DNA called telomeres control how long you live. We are now learning that it is your diet and lifestyle that shape your telomeres, not the other way around.
A detailed chemical model must generated to help support theories before we can decide what’s the truth behind the emergence of life on earth, and researchers at the Weizmann Institute have developed it.
Zika virus may be sexually transmissible for a shorter period than previously estimated, according to a new systematic review.