Science

Disruptive science can have a significant impact outside of our own domains of research and into our personal lives. Keeping abreast of these developments can help prepare and inspire.

Blinatumomab – Improving Outcomes for Children with Relapsed Leukaemia

The immunotherapy drug Blinatumomab has shown to be an effective treatment for children and young adults with relapsed B-cell acute lymphoblastic leukaemia in a clinical trial led by the Children’s Oncology Group, part of the National Cancer Institute USA, and presented at the annual meeting at the American Society of Haematology.

Huntington’s Therapy Found in Ancient Worms

A highly conserved mechanism in worms and humans has been discovered by researchers at Monash University that could provide a novel therapeutic approach for neurodegenerative diseases such as Huntington’s and Parkinson’s.

Genetic Cause of a Rare Type of Epilepsy Found

The cause of a rare type of familial epilepsy has been linked to two new gene mutations, as discovered by researchers from the Walter and Eliza Hall Institute. Published back-to-back in Nature Communications, Dr Mark Bennett, Dr Haloom Rafehi and Professor Melanie Bahlo from the Institute made this ground-breaking discovery as part of an international consortium.

“Junk DNA”: The New Place to Look for Cancer Risk

New research published in the British Journal of Cancer has identified a link between the so-called “junk DNA” and the risk of developing cancer. Junk DNA refers to regions of DNA that don’t code for proteins but are thought to play in a role in gene expression regulation

Epigenetics Found to Play a Role in Childhood Kidney Cancer

Researchers at the Wellcome Sanger Institute uncovered a possible pre-cancerous signature for Wilms’ tumour, a form of kidney cancer mainly affecting children under five years old. Published in Science, the research was the first to compare Wilms’ tumour tissue and healthy kidney tissue to identify any genetic changes that could possibly be predictive of disease progression.

The New Genomics “Hubble Space Telescope”

Researchers at the Centre for Genomic Regulation in Barcelona, Spain have developed a new type of genomics technology that can be used to investigate how species are related to each other, with a possibility of creating new drugs, foods, and materials at a much larger scale than ever before.

Autism and ADHD Have Shared Genetic Origins

Childhood neurodevelopmental disorders have now been shown to possess shared genetic roots. A study published in Nature Neuroscience has identified a new risk variant in the MAP1A gene for autism and ADHD.

New Mars Rover to Look for Fossilised Alien Life

An exploratory project to find fossil microbes on the Red Planet has been proposed between NASA and the European Space Agency (ESA). The possibility of finding alien life has long been an alluring concept for many and this new scheme intends to bring Martian soil to Earth for intensive study.

Registration for the Festival of Genomics 2020 Now Open

Returning for its 5th consecutive year, the 2020 Festival promises to be a unique experience, a crossroads for the entire genomics ecosystem to discover, meet, learn, have fun and celebrate. It is the largest genomics event in the UK and the fastest growing genomics event in the world. The Festival delivers incredible talks, speakers, cutting-edge content, inspirational topics, […]

Translating Metastasis Research into New Models and Therapies

Understanding and tackling metastatic cancer is the single biggest opportunity to improve outcomes for the most cancer patients. But it also represents a huge opportunity to (1) improve the development of existing cancer drugs, (2) reverse declining clinical success rates in oncology, (3) drive the development of new therapies, (4) treat more aggressive cancers and […]

Hiring and Beyond: How to Resource Data Scientists in your Business

In any field, data science is an emerging area where roles can be hard to define or quantify by hiring managers. For those looking to employ data scientists within their business, this role can lead to a wealth of unanswered questions. This chapter from our Data Solutions for Drug Development Report, sets out key tips […]

Scientists Engineer Proteins into Never-Ending Patterns

Scientists have engineered proteins to form fractal geometric shapes with never-ending patterns, closely resembling those found in nature. The protein patterns could have applications in next-generation biomaterials. Fractal geometric shapes make extremely useful biomaterials as they have large surface to volume ratios, allowing rapid exchange of materials. This makes them ideal for applications both in […]

Colour Changing Tattoos Can Sense Biomarkers

Scientists have developed tattoos that change colour depending on the interstitial fluid concentration of key biomarkers. The development is a step towards developing quicker diagnostics. The biomarkers studied were pH, glucose and albumin. Variation of blood pH can be indictive of a range of health conditions and glucose sensing is extremely useful for monitoring diabetes. […]