A new scientific innovation is set to help scientists understand the causes of cancer with greater speed and precision than ever before. Rather than looking at individual gene mutations on their own, scientists can now create models incorporating a number of mutations.
Disruptive science can have a significant impact outside of our own domains of research and into our personal lives. Keeping abreast of these developments can help prepare and inspire.
Consumer genetic sequencing, used to provide individuals with data about their ancestry and health, could identify more than half of Americans of European descent from anonymous samples, a new study has found.
Researchers at the Chinese Academy of Sciences have used two female mice to create offspring which subsequently went on to have healthy children of their own. While similar offspring were produced from two male mice, they did not survive for longer than a few days.
A new report from the University of Pennsylvania School of Veterinary Medicine has expanded what we know about the connection between myeloid-derived immunosuppressor cells (MDSCs) and aggressive disease. Their research has found that blocking the deltaNp63 protein on tumour cells which directs MDSCs to tumour and metastatic sites, or blocking the MDSCs themselves, reduces tumour growth and metastasis in a mouse model of triple-negative breast cancer (TNBC).
For the first time, scientists have performed prenatal gene editing to prevent a lethal metabolic disorder in laboratory animals, offering the potential to treat human congenital diseases before birth.
The development of the first automated DNA sequencers completely revolutionized the field of DNA sequencing and, eventually, made it possible to publish the first draft sequences of the human genome. Since then, a whole host of companies have developed their own approaches to DNA sequencing, resulting in a market that is filled with different possibilities […]
Scientists at Dana-Farber Cancer Institute have solved a mystery that has lingered ever since the dangers of the drug first became apparent: how did the drug produce such severe fetal harm?
With artificial intelligence, machines can now examine thousands of medical images for signs of disease. Will this technology replace doctors – or work side by side with them?
Scientists have long thought that regions of DNA called telomeres control how long you live. We are now learning that it is your diet and lifestyle that shape your telomeres, not the other way around.
A type of enzyme called matrix metalloproteinase could be key to the development of “smart” cancer drugs, according to new research.
GBA analysis is complicated by the presence of a nearby pseudogene. A new method is presented for sequencing GBA, using an amplicon including all coding regions and introns, on the MinION, enabling a fast and comprehensive assessment.