For the first time, scientists have changed human stem cells into functional insulin-producing cells in mice, potentially promising a breakthrough in treatment for those suffering from type 1 diabetes.
Disruptive science can have a significant impact outside of our own domains of research and into our personal lives. Keeping abreast of these developments can help prepare and inspire.
Genomics industry professionals working in the USA are the highest paid in the world and their UK colleagues earn on average less than half as much. This was one of the most striking findings from the second annual Genomics Industry Workforce survey report published this week by Front Line Genomics and Paramount Recruitment.
Scientists at the Institute of Neuroscience (ION) in China have reportedly used gene-editing technology to disable a certain gene vital to sleep-cycle in macaque monkeys. This prototype could create populations of genetically identical monkeys to allow scientists to better study the mechanisms of complex human disorders.
The Personal Genetics Education Project (pgEd) is an organisation which firmly believes in expanding genetics knowledge even further afield and increase awareness of the benefits and societal implications of personal genetics. We spoke to them about their goals, their concerns, and some of their biggest successes to date.
With so many talks and panels occurring across our four stages and Live Lounge, we understand that it can be pretty hard to pick out the most unmissable discussions at the festival this year. Given the conundrum, we thought we’d help out! We’ve selected a couple of talks and panels occurring across the two days which we think will be incredibly interesting and enormously informative for a whole range of people.
Data integration has been one of the major trends of the last few years, and one which will become ever-more important as the life sciences sectors progress further. Dr. Maya Ghoussaini, Genetic Analysis Team Leader at the Wellcome Sanger Institute, and Dr. Denise Carvalho-Silva, Scientific Outreach Lead at EMBL-EBI, both working at Open Targets, here discuss the importance of this process, and their own work within the realm of data integration.
SOPHiA GENETICS has successfully completed a $77 million funding round, the company recently announced at the JP Morgan Healthcare Conference in San Francisco.
A CRISPR study has determined how DNA times its own replication, something which until now has been unknown to scientists.
A modified version of CRISPR has been used to reverse genetic obesity in two different mouse models without editing any genes. The technique uses the guidance system in CRISPR to target certain genetic sequences and amplifies existing gene activity to ramp up protein production.
Personalised tumour-detecting cells from adult skin cells have been used to shrink brain tumours in mice by up to 5%, scientists have revealed. While the strategy has not yet been fully tested in people, it could in the future give doctors the ability to develop a custom treatment for certain cancer types.
Amgen and Entera Bio are partnering up to develop new treatments for inflammatory disease and certain other serious illnesses using the Entera drug discovery program. The platform will be used to develop oral formulations for one preclinical large molecule program which Amgen has selected. Entera’s CEO said the collaboration would be an important validation test of the platform technology.
The CCR5 gene has been researched by scientists since the 1990s, and has a number of roles which have not yet properly been uncovered. Loss of the gene’s function is known, however, to increase the risk of potentially fatal reactions to some diseases, and has shown an ability to enhance learning in mice.