Sequencing

The advancement of sequencing technology has had the singe biggest effect on genomics research. As it develops further, so does the scope of genomic research and applications.

Shareable Science: How the Loch Ness Monster could Help Save Marine Life

Our guest contributor Dr Neil Lamb continues his fortnighty Shareable Science Blog. Neil is the Vice President for Educational Outreach at the HudsonAlpha Institute for Biotechnology and Shareable Science will explore how genetics is relevant to people in their everyday lives.  Scientists from New Zealand’s Otago University called a news conference in early September 2019 […]

Child Cancer Patients are not Seeing the Full Benefits of Tumour Sequencing

51% of child cancer patients in a recent trial had gene mutations in their tumours that could be targeted by an existing adult cancer drug. However, due to clinical obstacles only 7% were able to receive the relevant drug, raising concerns about the lack of cancer therapies available for children. Treating cancer in children is […]

Has a DNA Study Solved the Mystery of the Loch Ness Monster?

Mysterious sightings of a giant creature in the lake have fascinated Loch Ness visitors for years. The fabled Lock Ness monster, or ‘Nessie’, has been speculated to be a prehistoric marine reptile, called a plesiosaurus, or a shark. However, a recent DNA study could shed some light on one of Scotland’s longest running legends. Scientists […]

Gene That Promotes Natural Short Sleep Identified

The gene that controls how much sleep a person needs to feel fully rested has been identified by researchers. Back in 2009 the researchers led by Ying-Hui Fu, PhD, discovered that those with the a mutation in their DEC2 gene averaged 6.25 hours sleep per night, compared to 8.06 hours in those without the mutation. […]

Genetic Mutation Significantly Increases Fruit Fly Lifespan

Fruit flies with a certain genetic mutation have significantly longer lifespans and better resistance to stresses than flies without the mutation. Fruit flies share a significant proportion of their genes with humans, making them good models to study human diseases and ageing. As the fruit flies usually live for about two months their lifespan is […]

New Blood Test Can Predict Cancer Progression

A new technique to analyse the tumour DNA present in patient’s blood circulations is an effective method to monitor breast cancer progression. The technique has been shown to give a hundred-fold improvement in the detection limit for tumour DNA. Analysis of the DNA that the tumour sheds into the bloodstream provides a non-invasive means of […]

Genomic Study of Komodo Dragons Shows Why They are Top Predators

A genomic study of Komodo dragons has shed light on their crucial genetic adaptations that have enabled them to become powerful apex predators. Komodo dragons are native to the Indonesian Islands, where they are top of the food chain. They can be up to 3m long, run at speeds of 20 kph and can take […]

Results of Melanoma Genetic Testing Motivate Positive Lifestyle Changes

Explaining to people that they have a high genetic risk for melanoma makes them choose positive lifestyle changes to reduce their risk, a new study has shown. Melanoma is a type of skin cancer to which certain people are predisposed to through genetic factors. These include having a family history of the disease and carrying […]

CRISPR Used to Find Genes that Protect Cells from Zika

A CRISPR technique has been used to identify genes in cells that enable them to survive infection of the Zika Virus. It is hoped that this development will lead to future treatments for Zika. Currently there is no vaccine or treatment specific to the Zika virus. If pregnant women contract the disease their unborn children […]

Drug-Resistant Malaria Spreads Across Asia

A genomics study has revealed that a strain of malaria resistant to both drugs used for treatment has spread rapidly across Asia.  Malaria causes approximately a million deaths worldwide in each year and is a serious public health issue, particularly in Asia. The widely used anti-malarial drugs dihydroartemisinin and piperaquine have been relatively effective treatments […]

Genetic Study Identifies Diabetes Gene in African Populations

The largest scale genomic study in Africa has identified a new gene that is linked to the onset of diabetes in African populations. Interestingly, the gene has not been found to be linked to diabetes in European populations.   In type 2 diabetes the body is able to produce insulin but the body’s cells do […]

False Genetic Testing Results Condemned by Doctors

The inaccuracy of a genetic test that gave false positives to patients has resulted in doctors calling for a crackdown on genetic testing. If a woman’s BCRA gene is faulty,  her risk of breast and ovarian cancer is much higher than average. People with a family history of these cancers are often tested to identify […]