Sequencing

The advancement of sequencing technology has had the singe biggest effect on genomics research. As it develops further, so does the scope of genomic research and applications.

Human genome sequencing on PromethION: characterization of structural variants and repetitive regions

  At the VIB-UAntwerp Center for Molecular Neurology, we apply sequencing technologies to elucidate the genetic etiology of neurodegenerative brain diseases such as Alzheimer Disease and Frontotemporal Dementia. Structural variation and repetitive regions are insufficiently characterized using currently dominant short-read sequencing technologies. Long-read sequencing on the Oxford Nanopore PromethION has the potential for a comprehensive […]

Sequencing Buyers’ Guide

The development of the first automated DNA sequencers completely revolutionized the field of DNA sequencing and, eventually, made it possible to publish the first draft sequences of the human genome. Since then, a whole host of companies have developed their own approaches to DNA sequencing, resulting in a market that is filled with different possibilities […]

Precision Medicine: A Global Initiative

Despite representing over 40% of the global population, Asians are vastly underrepresented in genetic databases contributing around 1%. We take a look at how FDNA, and other key players are changing this.

A WGS Workflow For the NHS

Researchers, led by scientists at University College London, have developed a novel paediatric whole genome sequencing workflow that could run within the current National Health Service system.

GSK and 23andMe Agree to $300M Deal

Pharmaceutical giant GlaxoSmithKline has bought a $300 million stake in genetic DTC testing company 23andMe to help further their genetics-based drug discovery.