Stem cells

Telomere Gene Holds Key to Pluripotency

A gene that codes for a telomere protein is the key to regulating stem cell pluripotency, new research shows. Pluripotent stem cells have the ability to differentiate into any type of specialised cell in the body. They hold huge potential for a range of regenerative medical treatments. Scientists have previously struggled to understand the genetic […]

Cyber Organoids Let Scientists Observe Cell Development

Scientists have successfully grown a ‘cyber organoid,’ a simplified organ formed from stem cells with integrated electrochemical sensors to observe its development. Organs are formed by the self-assembly of stem cells into complex 3D structures. However, due to the difficulty of monitoring this process there are still significant gaps in scientists’ understanding. Electrochemical sensors have […]

First Artificial Human Liver Created

Researchers have created the first artificial human liver model from genetically engineered human liver cells. It is hoped that the artificial liver will be an effective model to study fatty liver diseases. Non-alcoholic fatty liver disease (NAFLD) is a condition where fat builds up in the liver, eventually leading to liver failure. There is currently […]

Fleeting Genetic Changes Could Have Lasting Impact

Fleeting genetic changes observed in stem cells as they differentiate could shed light on the origin of certain genetic diseases. Scientists studying stem cell differentiation usually only compare the differences in gene expression between the fully undifferentiated and differentiated cells. However, new research has revealed that the fleeting genetic changes during cell development could have […]

Stem Cells Edited In Vivo For the First Time

Researchers have genetically modified stem cells inside the bodies of mice for the first time, in a study that could lead eventually to new potential for stem cell therapies. The study also shows potential for studying genetically-edited stem cells within the body, rather than in the lab.