Technology

CRUK Funds Development of POC Blood-Based Brain Cancer Test

Cancer Research UK (CRUK) has funded a project run by a team of researchers at the University of Bristol to develop a new blood-based test for early diagnosis of brain cancer. The researchers are planning to deploy the point-of-care (POC) assay based on a fluorescent nanophotonics platform, which is a platform that studies the behaviour […]

“We Need to have Resilience and Tolerance for Failure” – Interview with Guillermo Del Angel, Alexion Pharmaceuticals

Dr. Guillermo del Angel is currently Sr. Director for Data Science, Genomics and Bioinformatics at Alexion Pharmaceuticals. He has been leading research efforts focused on applying and developing different machine learning, genetics and data science approaches to improve rare disease target discovery, drug development, and patient/disease characterization FLG: Could you give us an introduction of […]

OCD Drug Designed by Artificial Intelligence Set to Enter Clinical Trials

A new drug created with artificial intelligence (AI) to treat patients with obsessive-compulsive disorder (OCD) will be entering human clinical trials this March – a first for AI. It has cut the drug development time from four and a half years to just 12 months, accelerating the time it typically takes to develop drugs for clinical trials.

Sequencing Buyers’ Guide

Get past the hype and bias in sequencing vendor marketing materials, and get an unbiased, highly informed view from a highly qualified professional whose job it is to evaluate sequencing technologies for a world leading healthcare and research institution – the Mayo Clinic. Get a base- to high-level understanding of the sequencing process, to give […]

Detecting Leukaemia with Artificial Intelligence

Researchers at the German Centre for Neurodegenerative Diseases (DZNE) and the University of Bonn have investigated the use of artificial intelligence to detect one of the most common forms of blood cancer – acute myeloid leukaemia (AML) – with high reliability. Published in iScience, the technique was used to analyse the expression of certain genes in cells of the blood.

George Church Robustly Defends his “DNA Dating App”

George Church of Harvard University has been under heavy scrutiny after news broke out of a new “DNA Dating App” he has been involved in developing, during a recent interview with 60 minutes. The news has led to a significant backlash from some quarters, including from some within the genomics community, that the app is unethical and represents a form of eugenics.

The Saliva Test to Detect Mouth and Throat Cancer

A new non-invasive method to detect the presence of human papilloma virus (HPV)-16 in saliva has been successfully used in a collaboration between Duke University, UCLA, and University of Birmingham. HPV-16 is a high-risk virus known to be an etiologic agent for the development of head and neck cancers, specifically with oropharyngeal caners (OPCs).

Deep Learning Technology Used to Decode Gene Interactions

Computer scientists at the Carnegie Mellon University in Pittsburgh have developed a digital method to transform massive amounts of gene expression data into something more image-like. Published in the Proceedings of the National Academy of Science, the scientists utilised an incredibly powerful deep learning method that has revolutionised methods such as facial recognition in recent years.

Registration for the Festival of Genomics 2020 Now Open

Returning for its 5th consecutive year, the 2020 Festival promises to be a unique experience, a crossroads for the entire genomics ecosystem to discover, meet, learn, have fun and celebrate. It is the largest genomics event in the UK and the fastest growing genomics event in the world. The Festival delivers incredible talks, speakers, cutting-edge content, inspirational topics, […]

Data-Driven Drug Development – Early Bird for D4 Europe Expires This Week

The early bird rate for our next event D4 (Data-Driven Drug Development) Europe expires this Friday, the only event where attendees will receive data, evidence and case studies from the world’s leading minds in pharma. This meeting is designed specifically to cater for senior people in pharma, combining strategic insights of value to IT/R&D leaders, […]

Cyber Organoids Let Scientists Observe Cell Development

Scientists have successfully grown a ‘cyber organoid,’ a simplified organ formed from stem cells with integrated electrochemical sensors to observe its development. Organs are formed by the self-assembly of stem cells into complex 3D structures. However, due to the difficulty of monitoring this process there are still significant gaps in scientists’ understanding. Electrochemical sensors have […]

Smartphone Used to Manipulate Brain Cells in Mice

Scientists have developed minimally invasive brain probes that can selectively deliver drugs in-vivo and stimulate cells with light. The probes can be wirelessly controlled from a smartphone. It is hoped that the probes will advance understanding of neurodegenerative disease by allowing the manipulation of brain circuits. Delivering drug infusions into the brain has previously been […]

Hiring and Beyond: How to Resource Data Scientists in your Business

In any field, data science is an emerging area where roles can be hard to define or quantify by hiring managers. For those looking to employ data scientists within their business, this role can lead to a wealth of unanswered questions. This chapter from our Data Solutions for Drug Development Report, sets out key tips […]