Technology

Festival of Genomics 2019 – The Importance of Data Integration in the Pharma Industry

Data integration has been one of the major trends of the last few years, and one which will become ever-more important as the life sciences sectors progress further. Dr. Maya Ghoussaini, Genetic Analysis Team Leader at the Wellcome Sanger Institute, and Dr. Denise Carvalho-Silva, Scientific Outreach Lead at EMBL-EBI, both working at Open Targets, here discuss the importance of this process, and their own work within the realm of data integration.

Festival of Genomics 2019: The Survival Guide

With just under two weeks till the festival, it’s time to start thinking logistics. The more scatter-brained of our readers needn’t worry, however: we’ve got everything you need covered in this handy guide, whether it’s things to remember before you arrive at the festival, the best things to do once there and the last couple of things to remember when it’s all done.

Genetics Unzipped: A New Science Podcast Exploring the World of Genes, Genomes and DNA

Genetics Unzipped, a new fortnightly podcast from the UK Genetics Society, has launched ahead of the society’s centenary celebrations throughout 2019. Presented by award-winning science writer and former Naked Genetics/Naked Scientists podcast host Kat Arney and produced by First Create The Media, Genetics Unzipped will bring you a wide range of stories from the world of genetics, genomics and DNA.

Optimising RNAscope® for Organotypic Cell Cultures

Laurent Neau, Lead Technician at the Philip Morris International Tissue Research Laboratory, talks about RNAscope®, a novel and increasingly popular technology developed by Advanced Cell Diagnostics, Inc. for the in situ analysis of RNA within fixed tissues, now optimised for use on 3D, organotypic cell cultures. Doing this has the potential to provide a window into gene expression as it occurs in the human body.

PetaGene Acquires Further $2.1 Million in Funding

Data compression startup PetaGene has closed a significant contract with biopharma company Romulus Capital, attracting £2.1 million in funding from that organisation and several other investors based in Silicon Valley and London. This investment round brings PetaGene’s total funding to $3.2 million.

Injectable RNA Treatment Helps Cure LCA Blindness

Data has shown the success of a new therapy to combat Leber congenital amaurosis (LCA), one of the leading causes of blindness in children, in LCA patients with CEP290 mutations. CEP290 acts as a barrier between two compartments of photoreceptor cells in the eye which convert light into signals, creating vision. Blindnesses caused by CEP290 […]

Most Orphan Drugs Performing Poorly, Report Finds

The latest annual report from Trinity Partners has found that orphan disease drugs often perform poorly at launch and continue to underachieve after three years of sales. At the other end of the spectrum, the most successful drugs on the market were for non-orphan diseases such as cancer and HIV.

Amgen and Entera Collaborate on Serious Illness Treatment Program

Amgen and Entera Bio are partnering up to develop new treatments for inflammatory disease and certain other serious illnesses using the Entera drug discovery program. The platform will be used to develop oral formulations for one preclinical large molecule program which Amgen has selected. Entera’s CEO said the collaboration would be an important validation test of the platform technology.

CRISPR Babies Could Face Unintended Consequences of Editing

The CCR5 gene has been researched by scientists since the 1990s, and has a number of roles which have not yet properly been uncovered. Loss of the gene’s function is known, however, to increase the risk of potentially fatal reactions to some diseases, and has shown an ability to enhance learning in mice.