Scientists from the University of Pennsylvania have created a test using gene-editing tools such as CRISPR to identify a gene variant responsible for severe hypertrophic cardiomyopathy (SHC). SHC is an often-familial disease which thickens heart walls and is linked to a variant in the TNNT2 gene.
Direct to consumer testing can potentially be quite dangerous without appropriate regulations and support to fully understand the implications of the information a consumer receives.
AstraZeneca and Cancer Research UK (CRUK) have announced that they will work together to open a new research centre in the UK, applying CRISPR and other functional genomics technologies to develop new cancer drugs. Specifically, the centre will study how genes and proteins interact with each other in cancer cells, and create disease models using genome-altering technologies based on this.
Despite what was previously thought, some mitochondrial DNA can be inherited from fathers as well as mothers, scientists have found. A study, published recently in PNAS, began when the Cincinnati Children’s Hospital Medical Centre tested a child showing signs of fatigue and muscle pain to see if he had a mitochondrial disorder.
Rady Children’s Hospital has launched a new, California State-funded initiative called Project Baby Bear to cover rWGS for critically ill newborns across the state.
US representatives are pressing genetic testing companies for details on their security systems and customer privacy policies.
Billionaire philanthropist Bill Gates has donated $30 million towards incentivising the development of an Alzheimer’s diagnostic test.
Clinical trials involving probiotics are failing to report on the safety and harms of these treatments.
Melanoma is it’s treatable if caught early enough. And a new blood test might be able to help with faster and easier diagnosis. Here’s what has to happen for the test to reach clinics:
The debate about the pros and cons of genetically screening embryos is deeply entrenched. Perhaps we should let couples decide?
Researchers have for the first time, used gene-editing tools in adult monkeys to disable a gene throughout much of the liver.